Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | FOLH1 | Q04609 | 9/20 | 0.34 |
| ▸ | TLR2 | O60603 | 1/20 | 0.33 |
| ▸ | FNTA | P49354 | 1/20 | 0.33 |
| ▸ | FNTB | P49356 | 1/20 | 0.33 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.33 |
| ▸ | FPR2 | P25090 | 1/20 | 0.32 |
| ▸ | C3AR1 | Q16581 | 1/20 | 0.32 |
| ▸ | S1PR2 | O95136 | 2/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.32 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.32 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.32 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.31 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.31 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.31 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3095595 | 0.96 | CA12 (0.36) | CA12CA1CA2CA9FOLH1 | |
| SCHEMBL3097941 | 0.91 | CA12 (0.39) | CA12CA1CA2CA9FPR2 | |
| SCHEMBL3091646 | 0.90 | CA12 (0.40) | CA12CA1CA2CA9FOLH1 | |
| SCHEMBL3109030 | 0.88 | CA12 (0.37) | CA12CA1CA2CA9FPR2 | |
| SCHEMBL3100588 | 0.87 | FPR2 (0.35) | CA12CA1CA2CA9FPR2 | |
| SCHEMBL3097853 | 0.86 | C3AR1 (0.43) | CA12CA1CA2CA9FOLH1 | |
| SCHEMBL3098952 | 0.82 | FOLH1 (0.42) | CA12CA1CA2CA9FOLH1 | |
| SCHEMBL2985776 | 0.82 | OTC (0.38) | CA12CA1CA2CA9FOLH1 | |
| SCHEMBL27743692 | 0.82 | OTC (0.38) | CA12CA1CA2CA9FOLH1 | |
| SCHEMBL3106289 | 0.81 | CA12 (0.41) | CA12CA1CA2CA9TLR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100247463-A1 | N-(PHOSPHONOALKYL)-AMINO ACIDS, DERIVATIVES THEREOF AND COMPOSITIONS AND METHODS OF USE | YU RUEY J | 2010-09-30 | — | — | US | claimed |