Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 4/20 | 0.55 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.55 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.55 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.55 |
| ▸ | THPO | P40225 | 1/20 | 0.55 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11453059 | 1.00 | PTGS1 (0.55) | PTGS1PTGS2SMN1; SMN2MAPTCXCR1 | |
| Water SCHEMBL11454953 | 0.98 | PTGS1 (0.54) | PTGS1PTGS2SMN1; SMN2MAPTCXCR1 | |
| Water SCHEMBL11454954 | 0.98 | PTGS1 (0.54) | PTGS1PTGS2SMN1; SMN2MAPTCXCR1 | |
| SCHEMBL11464120 | 0.91 | MAPT (0.52) | PTGS1PTGS2SMN1; SMN2MAPTCXCR1 | |
| SCHEMBL11472005 | 0.90 | CNR1 (0.48) | PTGS1PTGS2SMN1; SMN2MAPTCXCR1 | |
| SCHEMBL31006729 | 0.87 | ALDH1A1 (0.53) | SMN1; SMN2MAPTALDH1A1KDM4EHSD17B10 | |
| SCHEMBL17785165 | 0.85 | KMT2A (0.58) | SMN1; SMN2ALDH1A1HPGDMAPK1TDP1 | |
| SCHEMBL17785164 | 0.85 | KMT2A (0.58) | SMN1; SMN2ALDH1A1HPGDMAPK1TDP1 | |
| SCHEMBL669563 | 0.85 | MAPK13 (0.61) | PTGS1PTGS2SMN1; SMN2MAPTCXCR1 | |
| SCHEMBL669564 | 0.85 | MAPK13 (0.61) | PTGS1PTGS2SMN1; SMN2MAPTCXCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4223039-A | ANALGESICS | METABIO JOULLIE (FR) | 1980-09-16 | — | — | US | claimed |
| US-4223039-A | ANALGESICS | METABIO JOULLIE (FR) | 1980-09-16 | — | — | US | disclosed |