Pyrophosphoric Acid

Pyrophosphoric Acid

SCHEMBL3100835

C[C@H]1O[C@@H](n2ccc(N)nc2=O)[C@H](O)[C@@H]1O.O=P(O)(O)OP(=O)(O)O

nearest known ligand 0.57

Full drug profile on Sugi Atlas →

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.57
THRB P10828 1/20 0.57
MTOR P42345 1/20 0.57
MDM2 Q00987 1/20 0.57
NCOA1 Q15788 1/20 0.57
NCOA3 Q9Y6Q9 1/20 0.57
NT5E P21589 1/20 0.53
P2RY2 P41231 4/20 0.52
TSHR P16473 1/20 0.52
GLA P06280 1/20 0.52
P2RY6 Q15077 3/20 0.49
L3MBTL1 Q9Y468 1/20 0.48
POLB P06746 1/20 0.48
POLG P54098 2/20 0.46
P2RY4 P51582 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Triphosphate SCHEMBL31006154 0.95 P2RY2 (0.55) LMNATHRBMTORMDM2NCOA1
Phosphoric Acid SCHEMBL3100818 0.93 LMNA (0.62) LMNATHRBMTORMDM2NCOA1
Phosphoric Acid SCHEMBL1299876 0.93 LMNA (0.62) LMNATHRBMTORMDM2NCOA1
SCHEMBL4879682 0.90 LMNA (0.67) LMNATHRBMTORMDM2NCOA1
SCHEMBL399324 0.90 LMNA (0.67) LMNATHRBMTORMDM2NCOA1
SCHEMBL399323 0.90 LMNA (0.67) LMNATHRBMTORMDM2NCOA1
SCHEMBL10015791 0.90 LMNA (0.67) LMNATHRBMTORMDM2NCOA1
SCHEMBL3100871 0.86 LMNA (0.49) LMNATHRBMTORMDM2NCOA1
SCHEMBL3100908 0.86 LMNA (0.49) LMNATHRBMTORMDM2NCOA1
SCHEMBL1299881 0.85 LMNA (0.53) LMNATHRBMTORMDM2NCOA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8409594-B2 Solid oil-in-water emulsion OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2013-04-02 US disclosed
US-7794739-B2 composition for applying to skin containing at least one purine nucleic acid-related substance chosen from adenosine monophosphate and salt thereof, at least one pyrimidine nucleic acid-related substance chosen from uridine monophosphate and salt thereof, and at least one additive; anti-aging, anti-acne OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2010-09-14 US disclosed
US-7557093-B2 Composition for promoting collagen production OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2009-07-07 US disclosed
US-20070280979-A1 Solid Oil-In-Water Emulsion OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2007-12-06 US disclosed
EP-1842522-A1 SOLID OIL-IN-WATER EMULSION Otsuka Pharmaceutical Company, Limited (JP) 2007-10-10 EP disclosed
US-20070135374-A1 Adenosine 5-monophosphate and uridine 5-monophosphate; OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2007-06-14 US disclosed
EP-1671618-A1 COMPOSITION FOR PROMOTING COLLAGEN PRODUCTION OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2006-06-21 EP disclosed
US-20050222076-A1 Composition for cell proliferation OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2005-10-06 US disclosed
EP-1498101-A1 COMPOSITION FOR CELL PROLIFERATION Otsuka Pharmaceutical Company, Limited (JP) 2005-01-19 EP disclosed