SCHEMBL399323

SCHEMBL399323

C[C@H]1O[C@@H](n2ccc(N)nc2=O)[C@H](O)[C@@H]1O

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.67
THRB P10828 1/20 0.67
MTOR P42345 1/20 0.67
MDM2 Q00987 1/20 0.67
NCOA1 Q15788 1/20 0.67
NCOA3 Q9Y6Q9 1/20 0.67
NT5E P21589 1/20 0.55
L3MBTL1 Q9Y468 1/20 0.53
TSHR P16473 1/20 0.49
GLA P06280 1/20 0.49
PDE3A Q14432 3/20 0.47
PDE4D Q08499 1/20 0.47
SLC29A1 Q99808 1/20 0.47
P2RY2 P41231 1/20 0.47
CACNA1F O60840 2/20 0.45
ALB P02768 2/20 0.45
MAPT P10636 2/20 0.45
CACNA1D Q01668 2/20 0.45
CACNA1S Q13698 2/20 0.45
CACNA1C Q13936 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10015791 1.00 LMNA (0.67) LMNATHRBMTORMDM2NCOA1
SCHEMBL399324 1.00 LMNA (0.67) LMNATHRBMTORMDM2NCOA1
SCHEMBL4879682 1.00 LMNA (0.67) LMNATHRBMTORMDM2NCOA1
Phosphoric Acid SCHEMBL3100818 0.95 LMNA (0.62) LMNATHRBMTORMDM2NCOA1
Phosphoric Acid SCHEMBL1299876 0.95 LMNA (0.62) LMNATHRBMTORMDM2NCOA1
Pyrophosphoric Acid SCHEMBL3100835 0.90 LMNA (0.57) LMNATHRBMTORMDM2NCOA1
SCHEMBL24337513 0.90 LMNA (0.62) LMNATHRBMTORMDM2NCOA1
SCHEMBL14929500 0.90 LMNA (0.59) LMNATHRBMTORMDM2NCOA1
SCHEMBL10015807 0.90 LMNA (0.59) LMNATHRBMTORMDM2NCOA1
Triphosphate SCHEMBL31006154 0.88 P2RY2 (0.55) LMNATHRBMTORMDM2NCOA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 112 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118344418-A Improved process for controlling crystallization process of 5' -deoxycytidine acid 上海蔚之星生物科技有限公司 2024-07-16 CN claimed
CN-115581703-A Compound gemcitabine composition and application thereof 江苏集萃分子工程研究院有限公司 2023-01-10 CN claimed
JP-10330395-A None JP disclosed
US-20240352540-A1 DNAZYME FOR CLOSTRIDIUM DIFFICILE DETECTION MCMASTER UNIVERSITY (CA) 2024-10-24 US disclosed
CN-118344418-A Improved process for controlling crystallization process of 5' -deoxycytidine acid 上海蔚之星生物科技有限公司 2024-07-16 CN disclosed
CN-118344418-A Improved process for controlling crystallization process of 5' -deoxycytidine acid 上海蔚之星生物科技有限公司 2024-07-16 CN disclosed
CN-118344418-A Improved process for controlling crystallization process of 5' -deoxycytidine acid 上海蔚之星生物科技有限公司 2024-07-16 CN disclosed
EP-3851030-B1 MEDICAL DEVICE FOR ANALYTE MONITORING LABRADOR DIAGNOSTICS LLC (US) 2024-01-17 EP disclosed
CN-111377982-B Method for synthesizing decitabine key intermediate by solid acid catalysis 鲁南制药集团股份有限公司 2023-05-26 CN disclosed
CN-112209977-B Decitabine intermediate compound VI 鲁南制药集团股份有限公司 2023-05-26 CN disclosed
CN-112209976-B Decitabine intermediate compound V 鲁南制药集团股份有限公司 2023-05-26 CN disclosed
JP-H10330395-A 5'-DEOXY-CYTIDINE DERIVATIVE F HOFFMANN LA ROCHE AG 1998-12-15 JP disclosed
EP-0882734-A2 5'-Deoxy-cytidine derivatives F. HOFFMANN-LA ROCHE AG (CH) 1998-12-09 EP disclosed
EP-0882734-A2 5'-Deoxy-cytidine derivatives F. HOFFMANN-LA ROCHE AG (CH) 1998-12-09 EP disclosed
EP-0882734-A2 5'-Deoxy-cytidine derivatives F. HOFFMANN-LA ROCHE AG (CH) 1998-12-09 EP disclosed
CN-1201037-A 5'-deoxy-cytidine derivatives HOFFMANN LA ROCHE (CH) 1998-12-09 CN disclosed
CN-1201037-A 5'-deoxy-cytidine derivatives HOFFMANN LA ROCHE (CH) 1998-12-09 CN disclosed
EP-0493581-A1 RECOMBINANT GENE CODING FOR A PROTEIN HAVING AN ENDOCHITINASE ACTIVITY SANOFI (FR) 1992-07-08 EP disclosed
WO-1992001792-A1 RECOMBINANT GENE CODING FOR A PROTEIN HAVING AN ENDOCHITINASE ACTIVITY ELF SANOFI (FR) 1992-02-06 WO disclosed
US-4071680-A ANTITUMOR AGENTS HOFFMANN-LA ROCHE INC. (US) 1978-01-31 US disclosed