Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 3/20 | 0.43 |
| ▸ | PIP5K1C | O60331 | 2/20 | 0.43 |
| ▸ | PRKDC | P78527 | 2/20 | 0.41 |
| ▸ | BRAF | P15056 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | BTK | Q06187 | 1/20 | 0.37 |
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
| ▸ | ALPL | P05186 | 1/20 | 0.36 |
| ▸ | ALPI | P09923 | 1/20 | 0.36 |
| ▸ | ALPG | P10696 | 1/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.36 |
| ▸ | PIP5K1B | O14986 | 1/20 | 0.36 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.36 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29333379 | 1.00 | PIK3CA (0.43) | PIK3CAPIP5K1CPRKDCBRAFMAPT | |
| SCHEMBL29333377 | 0.85 | SCD5 (0.38) | MAPTKMT2AMEN1RAB9ANPSR1 | |
| SCHEMBL29333873 | 0.85 | SCD5 (0.38) | MAPTKMT2AMEN1RAB9ANPSR1 | |
| SCHEMBL29333749 | 0.84 | CCNC (0.35) | PIK3CAPIP5K1CBTKMTORJAK2 | |
| SCHEMBL29333474 | 0.83 | BTK (0.38) | BTKMTORJAK2 | |
| SCHEMBL31008591 | 0.83 | BTK (0.38) | BTKMTORJAK2 | |
| SCHEMBL31223623 | 0.81 | CNR1 (0.38) | MAPTKMT2AMCHR1CNR1BTK | |
| SCHEMBL31223708 | 0.81 | CNR1 (0.38) | MAPTKMT2AMCHR1CNR1BTK | |
| SCHEMBL29333761 | 0.79 | CYP1A2 (0.38) | PIK3CAPIP5K1CBTKMTORPIK3CD | |
| SCHEMBL29333552 | 0.79 | MAPK1 (0.40) | MAPTBTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240226114-A1 | INHIBITORS AND USES THEREOF | VIVIDION THERAPEUTICS, INC. | 2024-07-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240226114-A1 | INHIBITORS AND USES THEREOF | KEAP1, NQO1, NFE2L2 | PIK3CA 3512/4885PIP5K1C 3574/4885PRKDC 1814/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.