Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | PLAU | P00749 | 1/20 | 0.49 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.47 |
| ▸ | EGFR | P00533 | 1/20 | 0.47 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 2/20 | 0.46 |
| ▸ | KDM1A | O60341 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9001647 | 0.84 | ATM (0.72) | ATMKMT2AKDM4ETSHRHTT | |
| SCHEMBL493114 | 0.78 | KMT2A (0.75) | ATMKMT2AKDM4ETSHRHTT | |
| SCHEMBL9001653 | 0.78 | KMT2A (0.75) | ATMKMT2AKDM4ETSHRHTT | |
| SCHEMBL28867918 | 0.77 | KMT2A (0.64) | ATMKMT2AKDM4EHTTPLAU | |
| SCHEMBL9001650 | 0.77 | MAOA (0.63) | ATMKMT2AKDM4ETSHRHTT | |
| SCHEMBL6177291 | 0.77 | KDM1A (0.56) | ATMKMT2AKDM4ETSHRHTT | |
| SCHEMBL18615158 | 0.76 | ALDH1A1 (0.41) | TSHRHTTNPC1ALDH1A1HPGD | |
| SCHEMBL23558023 | 0.76 | ATM (0.58) | ATMKMT2AKDM4ETSHRHTT | |
| SCHEMBL257767 | 0.75 | KMT2A (0.66) | ATMKMT2AKDM4EHTTPLAU | |
| SCHEMBL2462295 | 0.75 | HSD17B2 (0.59) | ATMKMT2AKDM4ETSHRHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3774722-B1 | OPIOID RECEPTOR MODULATORS AND PRODUCTS AND METHODS RELATED THERETO | EPIODYNE INC (US) | 2024-07-24 | — | — | EP | disclosed |