Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | BTK | Q06187 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 2/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29218665 | 0.87 | BTK (0.57) | GAABTKNFKB1NFKB2RELA | |
| SCHEMBL29218668 | 0.87 | BTK (0.57) | GAABTKNFKB1NFKB2RELA | |
| SCHEMBL23274580 | 0.87 | BTK (0.57) | GAABTKNFKB1NFKB2RELA | |
| SCHEMBL31500135 | 0.87 | GAA (0.48) | GAABTKNFKB1NFKB2RELA | |
| SCHEMBL28803526 | 0.87 | ALDH1A1 (0.46) | GAABTKNFKB1NFKB2RELA | |
| SCHEMBL30279188 | 0.87 | ALDH1A1 (0.46) | GAABTKNFKB1NFKB2RELA | |
| SCHEMBL3621203 | 0.82 | GAA (0.54) | GAABTKNFKB1NFKB2RELA | |
| SCHEMBL2771992 | 0.82 | GAA (0.54) | GAABTKNFKB1NFKB2RELA | |
| SCHEMBL22630003 | 0.80 | GAA (0.47) | GAABTKNFKB1NFKB2RELA | |
| SCHEMBL18216175 | 0.80 | GAA (0.47) | GAABTKNFKB1NFKB2RELA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118076581-A | Iron death modulators, their preparation and use | 维泰瑞隆有限公司 | 2024-05-24 | — | — | CN | disclosed |