Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 2/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29218668 | 1.00 | BTK (0.57) | BTKGAANFKB1NFKB2RELA | |
| SCHEMBL29218665 | 1.00 | BTK (0.57) | BTKGAANFKB1NFKB2RELA | |
| SCHEMBL31008916 | 0.87 | GAA (0.45) | BTKGAANFKB1NFKB2RELA | |
| SCHEMBL28537514 | 0.87 | BTK (0.54) | BTKGAANFKB1NFKB2RELA | |
| SCHEMBL28540918 | 0.87 | BTK (0.54) | BTKGAANFKB1NFKB2RELA | |
| SCHEMBL2771992 | 0.83 | GAA (0.54) | BTKGAANFKB1NFKB2RELA | |
| SCHEMBL3621203 | 0.83 | GAA (0.54) | BTKGAANFKB1NFKB2RELA | |
| SCHEMBL30279188 | 0.83 | ALDH1A1 (0.46) | BTKGAANFKB1NFKB2RELA | |
| SCHEMBL28803526 | 0.83 | ALDH1A1 (0.46) | BTKGAANFKB1NFKB2RELA | |
| SCHEMBL30596812 | 0.80 | BTK (0.47) | BTKGAANFKB1NFKB2RELA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230107230-A1 | FLUORINE SUBSTITUTED CYCLOHEXENE ANALOGUES OF GAMMA- AMINOBUTYRIC ACID (GABA) | NORTHWESTERN UNIVERSITY | 2023-04-06 | — | — | US | disclosed |
| WO-2021081523-A1 | FLUORINE SUBSTITUTED CECLOHEXENE ANALOGOUES OF GAMMA-AMINOBUTYRIC ACID (GABA) | NORTHWESTERN UNIVERSITY (US) | 2021-04-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230107230-A1 | FLUORINE SUBSTITUTED CYCLOHEXENE ANALOGUES OF GAMMA- AMINOBUTYRIC ACID (GABA) | OAT, GABBR1, SLC1A2 | BTK 4603/4885GAA 51/4885NFKB1 2935/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.