Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNC | P24863 | 1/20 | 0.38 |
| ▸ | CDK8 | P49336 | 1/20 | 0.38 |
| ▸ | UMPS | P11172 | 2/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.31 |
| ▸ | CDK2 | P24941 | 2/20 | 0.31 |
| ▸ | CCNA1 | P78396 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16963927 | 0.70 | PROKR1 (0.30) | — | |
| SCHEMBL15565941 | 0.70 | UMPS (0.35) | UMPSHCAR2CCNA2CDK2CCNA1 | |
| SCHEMBL31010394 | 0.70 | CCNC (0.35) | CCNCCDK8 | |
| SCHEMBL15566755 | 0.68 | PARP1 (0.32) | UMPS | |
| SCHEMBL31010385 | 0.68 | CCNC (0.33) | CCNCCDK8 | |
| SCHEMBL27737484 | 0.66 | HCAR2 (0.39) | HCAR2LMNAPOLBCCNA2CDK2 | |
| SCHEMBL15566870 | 0.65 | MAPT (0.35) | UMPSPOLB | |
| SCHEMBL17224842 | 0.62 | HCAR2 (0.40) | HCAR2CCNA2CDK2CCNA1 | |
| SCHEMBL17479269 | 0.62 | HCAR2 (0.40) | HCAR2CCNA2CDK2CCNA1 | |
| SCHEMBL30486146 | 0.62 | MEN1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240252473-A1 | Sulfoximines as inhibitors of NaV1.8 | GRUENENTHAL GMBH (DE) | 2024-08-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240252473-A1 | Sulfoximines as inhibitors of NaV1.8 | SCN8A, SCN10A, SCN7A | CCNC 4731/4885CDK8 660/4885UMPS 2903/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.