Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.32 |
| ▸ | UMPS | P11172 | 1/20 | 0.32 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.31 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.30 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.30 |
| ▸ | TAB1 | Q15750 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15565941 | 0.83 | UMPS (0.35) | UMPSPDPK1 | |
| SCHEMBL15565869 | 0.74 | CA12 (0.40) | PARP1PARP2FFAR2 | |
| SCHEMBL21877671 | 0.70 | FFAR2 (0.34) | FFAR2 | |
| SCHEMBL31010386 | 0.68 | CCNC (0.38) | UMPS | |
| SCHEMBL25429970 | 0.67 | FFAR2 (0.32) | FFAR2 | |
| SCHEMBL13211644 | 0.65 | PDPK1 (0.45) | UMPSPDPK1 | |
| SCHEMBL29252887 | 0.65 | KDM1A (0.34) | PARP1PARP2 | |
| SCHEMBL28976633 | 0.65 | DGAT1 (0.38) | PARP1PARP2FFAR2 | |
| SCHEMBL28976697 | 0.65 | SCN10A (0.37) | PARP1PARP2FFAR2 | |
| SCHEMBL30281265 | 0.64 | JAK2 (0.35) | PARP1PARP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014024125-A1 | PYRAZOLO[4,3-D]PYRIMIDIN-7(6H)-ONE DERIVATIVES AS PDE9 INHIBITORS | CELON PHARMA S.A. (PL) | 2014-02-13 | — | — | WO | disclosed |