Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 4/20 | 0.49 |
| ▸ | CHRM2 known ✓ | P08172 | 2/20 | 0.49 |
| ▸ | CHRM1 known ✓ | P11229 | 2/20 | 0.49 |
| ▸ | SLC6A2 known ✓ | P23975 | 2/20 | 0.49 |
| ▸ | SLC6A3 known ✓ | Q01959 | 2/20 | 0.49 |
| ▸ | CHRM3 known ✓ | P20309 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | CASP2 | P42575 | 1/20 | 0.51 |
| ▸ | RAD52 | P43351 | 3/20 | 0.50 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.50 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.50 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.49 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.49 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.49 |
| ▸ | ESR1 | P03372 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1358752 | 0.98 | ACHE (0.50) | KMT2ASMN1; SMN2MEN1MAPTMAPK1 | |
| SCHEMBL29696465 | 0.92 | ACHE (0.61) | KMT2ASMN1; SMN2MEN1MAPTMAPK1 | |
| SCHEMBL30252245 | 0.92 | ACHE (0.61) | KMT2ASMN1; SMN2MEN1MAPTMAPK1 | |
| SCHEMBL31568165 | 0.89 | ACHE (0.40) | KMT2ASMN1; SMN2MEN1MAPTMAPK1 | |
| SCHEMBL30069411 | 0.83 | HTT (0.53) | KMT2ASMN1; SMN2MEN1MAPTMAPK1 | |
| Trifluoromethanesulfonic Acid SCHEMBL27642997 | 0.82 | ACHE (0.53) | KMT2ASMN1; SMN2MEN1MAPTMAPK1 | |
| Trifluoromethanesulfonamide SCHEMBL2295366 | 0.82 | ACHE (0.53) | KMT2ASMN1; SMN2MEN1MAPTMAPK1 | |
| Trifluoromethanesulfonic Acid SCHEMBL609162 | 0.82 | KCNH2 (0.53) | KMT2ASMN1; SMN2MEN1MAPTMAPK1 | |
| SCHEMBL933109 | 0.82 | KMT2A (0.32) | KMT2AACHECHRM2ADRA2AADORA3 | |
| SCHEMBL29382010 | 0.81 | LMNA (0.41) | KMT2ASMN1; SMN2MEN1MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118324668-A | Method for preparing bis (trifluoromethanesulfonyl) imine ionic liquid | 中船(邯郸)派瑞特种气体股份有限公司 | 2024-07-12 | — | — | CN | disclosed |