Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.39 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.37 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 4/20 | 0.35 |
| ▸ | INSR | P06213 | 1/20 | 0.35 |
| ▸ | IGF1R | P08069 | 1/20 | 0.35 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.35 |
| ▸ | PDE4A | P27815 | 2/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31014014 | 1.00 | HRH3 (0.40) | HRH3POLBGPR119PRMT5WDR77 | |
| SCHEMBL24914052 | 0.93 | HRH3 (0.41) | HRH3POLBGPR119PRMT5WDR77 | |
| SCHEMBL31013845 | 0.88 | ALDH1A1 (0.43) | ALDH1A1 | |
| SCHEMBL31013977 | 0.84 | ESR2 (0.42) | ALDH1A1NAMPTNR1H2 | |
| SCHEMBL31013913 | 0.84 | STS (0.35) | POLBGPR119ALDH1A1 | |
| SCHEMBL29168631 | 0.83 | MTHFD1 (0.39) | HRH3POLBPRMT5WDR77NAMPT | |
| SCHEMBL31013866 | 0.82 | ALDH1A1 (0.43) | HRH3ALDH1A1NR1H2 | |
| SCHEMBL31013948 | 0.82 | MGLL (0.40) | POLBGPR119ALDH1A1 | |
| SCHEMBL31014101 | 0.82 | MGLL (0.40) | POLBGPR119ALDH1A1 | |
| SCHEMBL31014020 | 0.81 | NAMPT (0.36) | GPR119ALDH1A1NAMPTNR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4651955-A1 | INHIBITOR COMPOUNDS | Neophore Limited (GB) | 2025-11-26 | — | — | EP | disclosed |
| WO-2024153947-A1 | INHIBITOR COMPOUNDS | Neophore Limited (GB) | 2024-07-25 | — | — | WO | disclosed |