Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 1/20 | 0.46 |
| ▸ | FPR2 | P25090 | 1/20 | 0.45 |
| ▸ | ACE | P12821 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | GGT1 | P19440 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.41 |
| ▸ | CTSG | P08311 | 2/20 | 0.41 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.41 |
| ▸ | CMA1 | P23946 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ANPEP | P15144 | 2/20 | 0.40 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.40 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3102568 | 0.90 | FPR2 (0.43) | FPR2SMN1; SMN2MEN1HTTKMT2A | |
| SCHEMBL3103119 | 0.88 | FPR2 (0.54) | MMEFPR2ACEMEN1KMT2A | |
| SCHEMBL2995625 | 0.81 | ANPEP (0.53) | MMEACEGGT1MEN1KMT2A | |
| SCHEMBL2995623 | 0.81 | ANPEP (0.53) | MMEACEGGT1MEN1KMT2A | |
| SCHEMBL3098722 | 0.81 | FPR2 (0.43) | FPR2TSHRMAPTMAPK1 | |
| SCHEMBL3098284 | 0.80 | FPR2 (0.52) | FPR2MAPTMAPK1GAAERAP1 | |
| SCHEMBL3091741 | 0.80 | PPARD (0.43) | FPR2TSHRMAPTMAPK1 | |
| SCHEMBL2208436 | 0.79 | MME (0.55) | MMEACESMN1; SMN2GGT1MEN1 | |
| SCHEMBL2208433 | 0.79 | MME (0.55) | MMEACESMN1; SMN2GGT1MEN1 | |
| SCHEMBL3098144 | 0.79 | ITGB2 (0.47) | ACESMN1; SMN2MEN1KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100247463-A1 | N-(PHOSPHONOALKYL)-AMINO ACIDS, DERIVATIVES THEREOF AND COMPOSITIONS AND METHODS OF USE | YU RUEY J | 2010-09-30 | — | — | US | claimed |