Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 7/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | PPARD | Q03181 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | GGH | Q92820 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3091741 | 0.89 | PPARD (0.43) | FPR2TSHRPPARDGGHMAPT | |
| SCHEMBL3109219 | 0.87 | FPR2 (0.34) | FPR2TSHRPPARDGGHMAPT | |
| SCHEMBL3097954 | 0.87 | GGH (0.49) | GGHFOLH1 | |
| SCHEMBL3098098 | 0.85 | FPR2 (0.43) | FPR2TSHRPPARDCA12CA1 | |
| SCHEMBL3094248 | 0.85 | PPARD (0.41) | FPR2TSHRPPARDMAPTMAPK1 | |
| SCHEMBL3105822 | 0.84 | FOLH1 (0.37) | FPR2TSHRPPARDCA12CA1 | |
| SCHEMBL3094655 | 0.84 | FPR2 (0.36) | FPR2TSHRPPARDGGHMAPT | |
| SCHEMBL3101487 | 0.84 | ALDH1A1 (0.40) | FPR2MAPK1CA12CA1CA2 | |
| SCHEMBL3102342 | 0.84 | CA2 (0.36) | FPR2TSHRPPARDGGHCA1 | |
| SCHEMBL3101417 | 0.83 | CA2 (0.40) | FPR2TSHRPPARDGGHMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100247463-A1 | N-(PHOSPHONOALKYL)-AMINO ACIDS, DERIVATIVES THEREOF AND COMPOSITIONS AND METHODS OF USE | YU RUEY J | 2010-09-30 | — | — | US | claimed |