Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB2 | P05107 | 2/20 | 0.47 |
| ▸ | ICAM1 | P05362 | 2/20 | 0.47 |
| ▸ | ITGAL | P20701 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | ACE | P12821 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | APAF1 | O14727 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3094241 | 0.91 | ALDH1A1 (0.47) | KDM4ECYP1A2CYP2C19ALDH1A1CYP3A4 | |
| SCHEMBL3091655 | 0.90 | ALOX15 (0.56) | ITGB2ICAM1ITGALALOX15KDM4E | |
| SCHEMBL2996583 | 0.85 | KMT2A (0.51) | ITGB2ICAM1ITGALALOX15KDM4E | |
| SCHEMBL3101652 | 0.83 | ECE1 (0.53) | ITGB2ICAM1ITGALALOX15KDM4E | |
| SCHEMBL7304271 | 0.81 | ERAP2 (0.51) | ACETP53 | |
| SCHEMBL3101425 | 0.79 | MME (0.46) | SMN1; SMN2KMT2AACEMEN1MAPT | |
| SCHEMBL3101626 | 0.78 | HTR2A (0.63) | KDM4ECYP1A2CYP2C19ALDH1A1KMT2A | |
| SCHEMBL468878 | 0.77 | ALOX15 (0.61) | ITGB2ICAM1ITGALALOX15KDM4E | |
| SCHEMBL22769512 | 0.77 | ALOX15 (0.61) | ITGB2ICAM1ITGALALOX15KDM4E | |
| SCHEMBL27818386 | 0.77 | ACE (0.54) | ITGB2ICAM1ITGALALOX15KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100247463-A1 | N-(PHOSPHONOALKYL)-AMINO ACIDS, DERIVATIVES THEREOF AND COMPOSITIONS AND METHODS OF USE | YU RUEY J | 2010-09-30 | — | — | US | claimed |