Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 14/20 | 0.40 |
| ▸ | TGM2 | P21980 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | GRM5 | P41594 | 1/20 | 0.35 |
| ▸ | ALPL | P05186 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31015728 | 0.88 | CDK2 (0.39) | CDK2TGM2MEN1KMT2AKDR | |
| SCHEMBL31015666 | 0.88 | CDK2 (0.40) | CDK2TGM2KDRGRM5 | |
| SCHEMBL31015756 | 0.82 | CDK2 (0.39) | CDK2TGM2KDRGRM5 | |
| SCHEMBL30872149 | 0.76 | TGM2 (0.46) | CDK2TGM2MEN1KMT2AKDR | |
| SCHEMBL26644600 | 0.76 | TGM2 (0.46) | CDK2TGM2MEN1KMT2AKDR | |
| SCHEMBL31015583 | 0.75 | DRD4 (0.41) | CDK2TGM2POLB | |
| SCHEMBL31015679 | 0.75 | TLK2 (0.43) | CDK2TGM2MEN1KMT2AKDR | |
| SCHEMBL31015727 | 0.74 | PDGFRB (0.45) | KDR | |
| SCHEMBL31015636 | 0.74 | KDR (0.39) | CDK2TGM2KDRPOLB | |
| SCHEMBL31015658 | 0.74 | KDR (0.39) | CDK2TGM2KDRPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024153246-A1 | SUBSTITUTED TRICYCLIC COMPOUND AND USE THEREOF | 海南先声再明医药股份有限公司 | 2024-07-25 | — | — | WO | disclosed |