Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 4/20 | 0.39 |
| ▸ | PDGFRB | P09619 | 3/20 | 0.39 |
| ▸ | PRKCB | P05771 | 1/20 | 0.37 |
| ▸ | PRKCA | P17252 | 1/20 | 0.37 |
| ▸ | PRKCH | P24723 | 1/20 | 0.37 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.37 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.37 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.37 |
| ▸ | CDK2 | P24941 | 5/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.33 |
| ▸ | TGM2 | P21980 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31015615 | 0.86 | CDK2 (0.34) | KDRPDGFRBCDK2TGM2MAOB | |
| SCHEMBL31015693 | 0.77 | CDK2 (0.35) | KDRCDK2KDM4EALDH1A1POLB | |
| SCHEMBL31015583 | 0.75 | DRD4 (0.41) | CDK2POLBTGM2 | |
| SCHEMBL31015636 | 0.74 | KDR (0.39) | KDRPDGFRBCDK2HTTKDM4E | |
| SCHEMBL31015666 | 0.74 | CDK2 (0.40) | KDRCDK2HTTKDM4EALDH1A1 | |
| SCHEMBL31015656 | 0.74 | CDK2 (0.40) | KDRCDK2POLBTGM2 | |
| SCHEMBL31015756 | 0.72 | CDK2 (0.39) | KDRCDK2KDM4EALDH1A1TGM2 | |
| SCHEMBL31015728 | 0.72 | CDK2 (0.39) | KDRCDK2POLBTGM2 | |
| SCHEMBL27310847 | 0.71 | L3MBTL1 (0.36) | KDRPDGFRBPRKCBPRKCAPRKCH | |
| SCHEMBL31015641 | 0.67 | CDK2 (0.40) | KDRCDK2KDM4EALDH1A1TGM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024153246-A1 | SUBSTITUTED TRICYCLIC COMPOUND AND USE THEREOF | 海南先声再明医药股份有限公司 | 2024-07-25 | — | — | WO | disclosed |