Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 9/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | ATG4B | Q9Y4P1 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31108715 | 0.81 | ATG4B (0.46) | KDRALDH1A1ATG4B | |
| SCHEMBL31015658 | 0.77 | KDR (0.39) | CDK2KDRALDH1A1KDM4EPOLB | |
| SCHEMBL31015615 | 0.67 | CDK2 (0.34) | CDK2KDR | |
| SCHEMBL32686674 | 0.66 | OGA (0.40) | KDRHPGD | |
| SCHEMBL28099487 | 0.65 | SLC6A4 (0.35) | ALDH1A1 | |
| SCHEMBL28099484 | 0.65 | SLC6A4 (0.35) | ALDH1A1 | |
| SCHEMBL30872149 | 0.65 | TGM2 (0.46) | CDK2KDR | |
| SCHEMBL26644600 | 0.65 | TGM2 (0.46) | CDK2KDR | |
| SCHEMBL31015656 | 0.65 | CDK2 (0.40) | CDK2KDRPOLB | |
| SCHEMBL31015666 | 0.65 | CDK2 (0.40) | CDK2KDRALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024153246-A1 | SUBSTITUTED TRICYCLIC COMPOUND AND USE THEREOF | 海南先声再明医药股份有限公司 | 2024-07-25 | — | — | WO | disclosed |