Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 5/20 | 0.42 |
| ▸ | PRKCA | P17252 | 1/20 | 0.39 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.39 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.39 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.39 |
| ▸ | KDM5A | P29375 | 2/20 | 0.39 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LPAR6 | P43657 | 1/20 | 0.38 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.38 |
| ▸ | LPAR4 | Q99677 | 1/20 | 0.38 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.38 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.38 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | GMNN | O75496 | 2/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28395366 | 0.99 | MAPT (0.44) | MAPK1MAPTLMNAPRKCAPRKCE | |
| SCHEMBL28504651 | 0.99 | MAPT (0.44) | MAPK1MAPTLMNAPRKCAPRKCE | |
| Sulfuric Acid SCHEMBL28580322 | 0.92 | MAPT (0.48) | MAPK1MAPTLMNAPRKCAPRKCE | |
| SCHEMBL28486823 | 0.90 | MAPT (0.53) | MAPK1MAPTLMNAPRKCAPRKCE | |
| Hydrochloric Acid SCHEMBL7213487 | 0.88 | MAPT (0.51) | MAPK1MAPTLMNAPRKCAPRKCE | |
| SCHEMBL28334151 | 0.81 | CES2 (0.37) | KDM5ADNM1THRATHRB | |
| SCHEMBL5940755 | 0.81 | CES2 (0.37) | KDM5ADNM1THRATHRB | |
| SCHEMBL29023591 | 0.81 | GGPS1 (0.37) | MAPTLPAR6LPAR1LPAR4LPAR5 | |
| SCHEMBL20339601 | 0.80 | LMNA (0.48) | MAPK1MAPTLMNAPRKCAPRKCE | |
| SCHEMBL19520238 | 0.80 | DNM1 (0.60) | MAPTLMNAPRKCAPRKCEPRKCQ |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118498337-B | Foundation construction method for silt geology | 辽宁城建集团有限公司 | 2024-10-01 | — | — | CN | disclosed |
| CN-118498337-A | Foundation construction method for silt geology | 辽宁城建集团有限公司 | 2024-08-16 | — | — | CN | disclosed |