Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MET | P08581 | 5/20 | 0.43 |
| ▸ | AXL | P30530 | 8/20 | 0.41 |
| ▸ | MERTK | Q12866 | 8/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.39 |
| ▸ | TYRO3 | Q06418 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31316523 | 0.90 | MET (0.47) | MEN1KMT2AMETAXLMERTK | |
| SCHEMBL14968986 | 0.88 | KDM4E (0.45) | MEN1KMT2AMETAXLMERTK | |
| SCHEMBL14969213 | 0.86 | MET (0.45) | METAXLMERTKHPGDALDH1A1 | |
| SCHEMBL21777695 | 0.84 | KDM4E (0.43) | METAXLMERTKHPGDALDH1A1 | |
| SCHEMBL30672485 | 0.83 | KMT2A (0.49) | MEN1KMT2AHPGDALDH1A1KDM4E | |
| SCHEMBL23071014 | 0.81 | KDM4E (0.46) | METAXLMERTKHPGDALDH1A1 | |
| SCHEMBL14969072 | 0.79 | MET (0.48) | METAXLMERTKHPGDALDH1A1 | |
| SCHEMBL23081448 | 0.79 | POLB (0.40) | MEN1KMT2AMETAXLMERTK | |
| SCHEMBL29814385 | 0.78 | LMNA (0.47) | MEN1KMT2AHPGDALDH1A1KDM4E | |
| SCHEMBL30031388 | 0.78 | AXL (0.52) | METAXLMERTKTYRO3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118388417-A | Pyrimidine derivative and preparation method and application thereof | 河北科技大学 | 2024-07-26 | — | — | CN | disclosed |