SCHEMBL310167

SCHEMBL310167

Nc1cc(F)ccn1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29708985 1.00
Hydrochloric Acid SCHEMBL17593273 0.97
Ethylamine SCHEMBL16584894 0.89 NOS3 (0.53)
SCHEMBL1255161 0.84 NOS3 (0.44)
Trifluoroacetic Acid SCHEMBL18760033 0.82 GABRP (0.50)
SCHEMBL2320602 0.75 DYRK1A (0.50)
SCHEMBL29432660 0.75 DYRK1A (0.59)
SCHEMBL21001790 0.75 DYRK1A (0.59)
SCHEMBL3282282 0.74
SCHEMBL13635718 0.72 NOS3 (0.50)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 836 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119432148-A Perovskite ink, perovskite film and battery device 云南大学 2025-02-14 CN claimed
CN-112250622-B Preparation method of 4-fluoropyridine-2-amine 山东省海洋化工科学研究院 2022-05-27 CN claimed
CN-112047942-B Synthesis method of 7-fluoroimidazo [1,2-A ] pyridine 都创(上海)医药科技股份有限公司 2022-01-18 CN claimed
WO-2021159993-A1 INHIBITORS OF INTERLEUKIN-1 RECEPTOR ASSOCIATED KINASE (IRAK) /FMS-LIKE RECEPTOR TYROSINE KINASE (FLT3), PHARMACEUTICAL PRODUCTS THEREOF, AND METHODS THEREOF PHARMABLOCK SCIENCES (NANJING) , INC. (CN) 2021-08-19 WO claimed
CN-112552233-A Synthetic method of 2-amino-4-fluoropyridine 镇江卡博医药科技有限公司 2021-03-26 CN claimed
CN-112250622-A Preparation method of 4-fluoropyridine-2-amine 山东省海洋化工科学研究院 2021-01-22 CN claimed
CN-112047942-A Synthesis method of 7-fluoroimidazo [1,2-A ] pyridine 都创(上海)医药科技有限公司 2020-12-08 CN claimed
CN-111635401-A Copper complex promoted 7-fluoroimidazo [1,2-a ] pyridine synthesis method 镇江卡博医药科技有限公司 2020-09-08 CN claimed
US-8309735-B2 Heterocyclic compounds for the inhibition of integrins and use thereof SHIRE ORPHAN THERAPIES GMBH (DE) 2012-11-13 US claimed
US-20090203745-A1 HETEROCYCLIC COMPOUNDS FOR THE INHIBITION OF INTEGRINS AND USE THEREOF JERINI AG (DE) 2009-08-13 US claimed
US-20090104116-A1 COMPOUNDS FOR THE INHIBITION OF INTEGRINS AND USE THEREOF JERINI AG (DE) 2009-04-23 US claimed
EP-2024357-A2 NEW HETEROCYCLIC COMPOUNDS FOR THE INHIBITION OF INTEGRINS AND USE THEREOF Jereni AG (DE) 2009-02-18 EP claimed
EP-1979342-A1 COMPOUNDS FOR THE INHIBITION OF INTEGRINS AND USE THEREOF Jerini AG (DE) 2008-10-15 EP claimed
WO-2007131764-A2 NEW HETEROCYCLIC COMPOUNDS FOR THE INHIBITION OF INTEGRINS AND USE THEREOF JERINI AG (DE) 2007-11-22 WO claimed
WO-2007088041-A1 COMPOUNDS FOR THE INHIBITION OF INTEGRINS AND USE THEREOF JERINI AG (DE) 2007-08-09 WO claimed
US-20260144881-A1 HPK1 TARGETING COMPOUNDS AND USES THEREOF ARVINAS OPERATIONS, INC. (US) 2026-05-28 US disclosed
EP-4027995-B1 HPK1 ANTAGONISTS AND USES THEREOF NIMBUS SATURN INC (US) 2026-05-27 EP disclosed
EP-0120589-B1 IMIDAZO-HETEROCYCLIC COMPOUNDS, PROCESSES FOR PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1988-06-08 EP disclosed
US-4621084-A CARDIOTONIC, ANTIULCER FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1986-11-04 US disclosed
EP-0120589-A1 Imidazo-heterocyclic compounds, processes for preparation thereof and pharmaceutical composition comprising the same FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1984-10-03 EP disclosed