Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 4/20 | 0.35 |
| ▸ | CLK4 | Q9HAZ1 | 4/20 | 0.35 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.35 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | RIPK2 | O43353 | 2/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | SPPL2A | Q8TCT8 | 1/20 | 0.32 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.32 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31043183 | 0.81 | RIPK2 (0.33) | DYRK1ACLK4PRMT5WDR77ALDH1A1 | |
| SCHEMBL31043156 | 0.81 | RIPK2 (0.33) | DYRK1ACLK4PRMT5WDR77ALDH1A1 | |
| SCHEMBL31424095 | 0.81 | RIPK2 (0.33) | DYRK1ACLK4PRMT5WDR77ALDH1A1 | |
| SCHEMBL31043230 | 0.81 | RIPK2 (0.33) | DYRK1ACLK4PRMT5WDR77ALDH1A1 | |
| SCHEMBL25324534 | 0.78 | ALDH1A1 (0.34) | DYRK1ACLK4PRMT5WDR77ALDH1A1 | |
| SCHEMBL25324531 | 0.78 | ALDH1A1 (0.34) | DYRK1ACLK4PRMT5WDR77ALDH1A1 | |
| SCHEMBL25913598 | 0.78 | ALDH1A1 (0.34) | DYRK1ACLK4PRMT5WDR77ALDH1A1 | |
| SCHEMBL25327271 | 0.78 | ALDH1A1 (0.34) | DYRK1ACLK4PRMT5WDR77ALDH1A1 | |
| SCHEMBL30522987 | 0.78 | ALDH1A1 (0.34) | DYRK1ACLK4PRMT5WDR77ALDH1A1 | |
| SCHEMBL24363885 | 0.77 | CHRNB2 (0.44) | DYRK1ACLK4ALDH1A1HSD17B10RIPK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118359604-A | Protein arginine methyltransferase inhibitors | 华润医药研究院（深圳）有限公司 | 2024-07-19 | — | — | CN | disclosed |