Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JUN | P05412 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 2/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29988880 | 0.94 | NFKB1 (0.48) | JUNNFKB1NFKB2RELAPOLB | |
| Formic Acid SCHEMBL30465837 | 0.89 | NFKB1 (0.47) | JUNNFKB1NFKB2RELAPOLB | |
| Trifluoroacetic Acid SCHEMBL30498406 | 0.84 | JUN (0.50) | JUNNFKB1NFKB2RELAPOLB | |
| SCHEMBL667384 | 0.81 | NFKB1 (0.51) | JUNNFKB1NFKB2RELAPOLB | |
| Formic Acid SCHEMBL29166004 | 0.73 | GAA (0.42) | JUNNFKB1NFKB2RELAPOLB | |
| SCHEMBL31306809 | 0.71 | P2RX7 (0.52) | JUNNFKB1NFKB2RELAPOLB | |
| SCHEMBL8600253 | 0.71 | P2RX7 (0.52) | JUNNFKB1NFKB2RELAPOLB | |
| SCHEMBL6983154 | 0.70 | JUN (0.48) | JUNNFKB1NFKB2RELAPOLB | |
| SCHEMBL4155438 | 0.70 | JUN (0.48) | JUNNFKB1NFKB2RELAPOLB | |
| SCHEMBL6418676 | 0.70 | JUN (0.51) | JUNNFKB1NFKB2RELAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118401516-A | TYK2 inhibitors, compositions and methods thereof | 凌科药业(杭州)有限公司 | 2024-07-26 | — | — | CN | disclosed |