Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | NR4A2 | P43354 | 3/20 | 0.50 |
| ▸ | RXRA | P19793 | 3/20 | 0.50 |
| ▸ | RXRB | P28702 | 3/20 | 0.50 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.50 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.50 |
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1503527 | 0.82 | PKM (0.53) | PKMNR4A2RXRARXRBNR4A1 | |
| SCHEMBL12607351 | 0.80 | PKM (0.47) | PKMNR4A2RXRARXRBNR4A1 | |
| SCHEMBL8011558 | 0.79 | PKM (0.58) | PKMNR4A2RXRARXRBNR4A1 | |
| SCHEMBL13337494 | 0.78 | PKM (0.49) | PKMNR4A2RXRARXRBNR4A1 | |
| SCHEMBL13337424 | 0.78 | RXRA (0.50) | PKMNR4A2RXRARXRBNR4A1 | |
| SCHEMBL30172106 | 0.78 | PKM (0.56) | PKMNR4A2RXRARXRBNR4A1 | |
| SCHEMBL4398919 | 0.78 | PKM (0.56) | PKMNR4A2RXRARXRBNR4A1 | |
| SCHEMBL13337470 | 0.77 | RXRA (0.49) | PKMNR4A2RXRARXRBNR4A1 | |
| SCHEMBL15235705 | 0.76 | CA12 (0.48) | PKMNR4A2RXRARXRBNR4A1 | |
| SCHEMBL15235702 | 0.76 | CA12 (0.48) | PKMNR4A2RXRARXRBNR4A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4622947-A1 | ENAMINE N-OXIDE TOOLS FOR TARGET IDENTIFICATION APPLICATIONS | Dana-Farber Cancer Institute, Inc. (US) | 2025-10-01 | — | — | EP | disclosed |
| WO-2024112754-A1 | ENAMINE N-OXIDE TOOLS FOR TARGET IDENTIFICATION APPLICATIONS | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2024-05-30 | — | — | WO | disclosed |