Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 16/20 | 0.41 |
| ▸ | FPR1 | P21462 | 9/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | F10 | P00742 | 1/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31019157 | 0.94 | MMP1 (0.40) | FPR2FPR1MMP1 | |
| SCHEMBL23168555 | 0.87 | FPR2 (0.43) | FPR2FPR1F10 | |
| SCHEMBL6817997 | 0.82 | FPR2 (0.49) | FPR2FPR1F2F10PRSS1 | |
| SCHEMBL5021029 | 0.82 | FPR2 (0.49) | FPR2FPR1F2F10PRSS1 | |
| SCHEMBL14022306 | 0.82 | FPR2 (0.45) | FPR2FPR1F2F10PRSS1 | |
| SCHEMBL18955315 | 0.81 | FPR2 (0.63) | FPR2FPR1 | |
| SCHEMBL18963928 | 0.81 | FPR2 (0.48) | FPR2FPR1F2F10PRSS1 | |
| SCHEMBL23168389 | 0.81 | FPR2 (0.56) | FPR2FPR1F2F10PRSS1 | |
| SCHEMBL18963926 | 0.81 | FPR2 (0.48) | FPR2FPR1F2F10PRSS1 | |
| SCHEMBL22650382 | 0.80 | FPR2 (0.43) | FPR2FPR1F2F10PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240245673-A1 | Papain-like protease (PLpro) inhibitors | PFIZER INC. (US) | 2024-07-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240245673-A1 | Papain-like protease (PLpro) inhibitors | PREP, PEPD, ACE | FPR2 1964/4885FPR1 494/4885F2 576/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.