Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 16/20 | 0.49 |
| ▸ | FPR1 | P21462 | 5/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | F2 | P00734 | 1/20 | 0.43 |
| ▸ | F10 | P00742 | 1/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6817997 | 1.00 | FPR2 (0.49) | FPR2FPR1KMT2AL3MBTL1F2 | |
| SCHEMBL7414725 | 0.93 | FPR2 (0.54) | FPR2FPR1KMT2AL3MBTL1 | |
| SCHEMBL7933692 | 0.93 | FPR2 (0.54) | FPR2FPR1KMT2AL3MBTL1 | |
| SCHEMBL7414726 | 0.93 | FPR2 (0.54) | FPR2FPR1KMT2AL3MBTL1 | |
| Hydrochloric Acid SCHEMBL7939389 | 0.91 | FPR2 (0.53) | FPR2FPR1KMT2AL3MBTL1 | |
| SCHEMBL14022306 | 0.89 | FPR2 (0.45) | FPR2FPR1F2F10PRSS1 | |
| SCHEMBL23168389 | 0.88 | FPR2 (0.56) | FPR2FPR1F2F10PRSS1 | |
| SCHEMBL18963926 | 0.88 | FPR2 (0.48) | FPR2FPR1F2F10PRSS1 | |
| SCHEMBL18963928 | 0.88 | FPR2 (0.48) | FPR2FPR1F2F10PRSS1 | |
| SCHEMBL18955315 | 0.87 | FPR2 (0.63) | FPR2FPR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8569507-B2 | N-(2-oxo-1-phenylpiperidin-3-yl)sulfonamides for the identification of biological and pharmacological activity | INSTITUT UNIV. DE CIENCIA I TECHNOLOGIA, S.A. (ES) | 2013-10-29 | — | — | US | disclosed |
| US-20120142930-A1 | N-(2-OXO-1-PHENYLPIPERIDIN-3-YL)SULFONAMIDES FOR THE IDENTIFICATION OF BIOLOGICAL AND PHARMACOLOGICAL ACTIVITY | AMIRA THERAPEUTICS, S.L. (ES) | 2012-06-07 | — | — | US | disclosed |
| US-20120129888-A1 | LIBRARIES OF N-(2-OXO-1-PHENYLPIPERIDIN-3-YL)SULFONAMIDES FOR DRUG DISCOVERY | INSTITUT UNIV. DE CIENCIA I TECNOLOGIA, S. A. (ES) | 2012-05-24 | — | — | US | disclosed |
| US-20120122950-A1 | LIBRARIES OF 1-(SULFONYL)-N-PHENYLPYRROLIDINE-2-CARBOXAMIDES FOR DRUG DISCOVERY | INSTITUT UNIV. DE CIENCIA I TECNOLOGIA, S. A. (ES) | 2012-05-17 | — | — | US | disclosed |
| US-20120122708-A1 | LIBRARIES OF N-(2-OXO-1-PHENYLPIPERIDIN-3-YL)SULFONAMIDES FOR THE IDENTIFICATION OF BIOLOGICAL AND PHARMACOLOGICAL ACTIVITY | INSTITUT UNIV. DE CIENCIA I TECNOLOGIA, S. A. (ES) | 2012-05-17 | — | — | US | disclosed |
| US-20120122709-A1 | LIBRARIES OF 1-(SULFONYL)-N-PHENYLPYRROLIDINE-2-CARBOXAMIDES FOR THE IDENTIFICATION OF BIOLOGICAL AND PHARMACOLOGICAL ACTIVITY | INSTITUT UNIV. DE CIENCIA I TECNOLOGIA, S. A. (ES) | 2012-05-17 | — | — | US | disclosed |
| US-20100121048-A1 | Cyclic Amine Compound and Use Thereof for the Prophylaxis or Treatment of Hypertension | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-05-13 | — | — | US | disclosed |
| US-20100121048-A1 | Cyclic Amine Compound and Use Thereof for the Prophylaxis or Treatment of Hypertension | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-05-13 | — | — | US | disclosed |
| WO-2007094513-A2 | CYCLIC AMINE COMPOUND AND USE THEREOF FOR THE PROPHYLAXIS OR TREATMENT OF HYPERTENSION | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-08-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100121048-A1 | Cyclic Amine Compound and Use Thereof for the Prophylaxis or Treatment of Hypertension | REN, AGTR1, AGTR2 | FPR2 2109/4885FPR1 1383/4885KMT2A 952/4885 |
| US-20120142930-A1 | N-(2-OXO-1-PHENYLPIPERIDIN-3-YL)SULFONAMIDES FOR THE IDENTIFICATION OF BIOLOGICAL AND PHARMACOLOGICAL ACTIVITY | TPX2, TPST2, AADAC | FPR2 300/4885FPR1 629/4885KMT2A 3817/4885 |
| US-20120122708-A1 | LIBRARIES OF N-(2-OXO-1-PHENYLPIPERIDIN-3-YL)SULFONAMIDES FOR THE IDENTIFICATION OF BIOLOGICAL AND PHARMACOLOGICAL ACTIVITY | AADAC, TPST2, SYNJ2 | FPR2 716/4885FPR1 1558/4885KMT2A 3771/4885 |
| US-20120129888-A1 | LIBRARIES OF N-(2-OXO-1-PHENYLPIPERIDIN-3-YL)SULFONAMIDES FOR DRUG DISCOVERY | TPX2, ANKRD52, NCS1 | FPR2 919/4885FPR1 1846/4885KMT2A 3707/4885 |
| US-20120122709-A1 | LIBRARIES OF 1-(SULFONYL)-N-PHENYLPYRROLIDINE-2-CARBOXAMIDES FOR THE IDENTIFICATION OF BIOLOGICAL AND PHARMACOLOGICAL ACTIVITY | AADAC, NCS1, CATSPER1 | FPR2 2385/4885FPR1 2616/4885KMT2A 3191/4885 |
| US-20120122950-A1 | LIBRARIES OF 1-(SULFONYL)-N-PHENYLPYRROLIDINE-2-CARBOXAMIDES FOR DRUG DISCOVERY | NCS1, AADAC, CATSPER1 | FPR2 2811/4885FPR1 2962/4885KMT2A 2642/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.