Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | MYC | P01106 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | PDE5A | O76074 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 3/20 | 0.31 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31019357 | 1.00 | ALDH1A1 (0.39) | ALDH1A1MYCMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL31019364 | 0.87 | ALDH1A1 (0.39) | ALDH1A1MYCMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL31019365 | 0.76 | ALDH1A1 (0.41) | ALDH1A1MYCMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL31019366 | 0.73 | ALDH1A1 (0.39) | ALDH1A1MYCMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL14471069 | 0.72 | ALDH1A1 (0.47) | ALDH1A1MYCMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL6923611 | 0.70 | ALDH1A1 (0.36) | ALDH1A1MEN1KMT2AKDM4ETDP1 | |
| SCHEMBL30625210 | 0.69 | ALDH1A1 (0.41) | ALDH1A1MYCMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL30848123 | 0.69 | ERN1 (0.35) | ALDH1A1MEN1KMT2ASMN1; SMN2HDAC1 | |
| SCHEMBL1003974 | 0.67 | KDM4E (0.42) | ALDH1A1MEN1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL28356853 | 0.67 | MYC (0.50) | ALDH1A1MYCKDM4ERAB9ATPMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024163752-A1 | HETEROCYCLIC COMPOUNDS AS PI3Kα INHIBITORS | SYNNOVATION THERAPEUTICS, INC. (US) | 2024-08-08 | — | — | WO | disclosed |