Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MYC | P01106 | 1/20 | 0.36 |
| ▸ | ERN1 | O75460 | 7/20 | 0.36 |
| ▸ | PLAU | P00749 | 2/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | F10 | P00742 | 1/20 | 0.33 |
| ▸ | PLG | P00747 | 1/20 | 0.33 |
| ▸ | PLAT | P00750 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | XDH | P47989 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31019365 | 0.76 | ALDH1A1 (0.41) | ALDH1A1MYCPLAUF2F10 | |
| SCHEMBL304092 | 0.75 | ERN1 (0.41) | ALDH1A1MYCERN1LMNACYP3A4 | |
| SCHEMBL31019357 | 0.73 | ALDH1A1 (0.39) | ALDH1A1MYCLMNAMAPTKDM4E | |
| SCHEMBL31019355 | 0.73 | ALDH1A1 (0.39) | ALDH1A1MYCLMNAMAPTKDM4E | |
| SCHEMBL31019364 | 0.73 | ALDH1A1 (0.39) | ALDH1A1MYCPLAUF2F10 | |
| SCHEMBL14471069 | 0.72 | ALDH1A1 (0.47) | ALDH1A1MYCF10LMNAMAPT | |
| SCHEMBL12581708 | 0.71 | CYP3A4 (0.46) | ALDH1A1ERN1CYP3A4MAPT | |
| SCHEMBL16207565 | 0.71 | ERN1 (0.34) | ALDH1A1MYCERN1LMNACYP3A4 | |
| SCHEMBL30625210 | 0.69 | ALDH1A1 (0.41) | ALDH1A1MYCPLAUF2F10 | |
| SCHEMBL31426164 | 0.69 | USP2 (0.38) | ALDH1A1ERN1LMNACYP3A4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024163752-A1 | HETEROCYCLIC COMPOUNDS AS PI3Kα INHIBITORS | SYNNOVATION THERAPEUTICS, INC. (US) | 2024-08-08 | — | — | WO | disclosed |