⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6046210 | 0.72 | — | — | |
| SCHEMBL8283279 | 0.70 | — | — | |
| SCHEMBL24852589 | 0.70 | — | — | |
| SCHEMBL24851905 | 0.70 | — | — | |
| Hydrochloric Acid SCHEMBL31019532 | 0.68 | RAB9A (0.31) | — | |
| SCHEMBL23997236 | 0.65 | PER2 (0.40) | — | |
| SCHEMBL31266652 | 0.65 | MAPK1 (0.38) | — | |
| SCHEMBL18367208 | 0.64 | HRH3 (0.37) | — | |
| SCHEMBL24818589 | 0.63 | PER2 (0.38) | — | |
| SCHEMBL9697645 | 0.62 | PER2 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240254118-A1 | PRMT5 INHIBITORS AND USES THEREOF | GILEAD SCIENCES, INC. | 2024-08-01 | — | — | US | disclosed |