Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 7/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 6/20 | 0.33 |
| ▸ | PSEN1 | P49768 | 4/20 | 0.33 |
| ▸ | PSEN2 | P49810 | 4/20 | 0.33 |
| ▸ | APH1B | Q8WW43 | 4/20 | 0.33 |
| ▸ | NCSTN | Q92542 | 4/20 | 0.33 |
| ▸ | APH1A | Q96BI3 | 4/20 | 0.33 |
| ▸ | PSENEN | Q9NZ42 | 4/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | PPARD | Q03181 | 1/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30428083 | 0.88 | TRPA1 (0.36) | PTGS2PTGS1TRPA1 | |
| SCHEMBL31019956 | 0.82 | PTGS2 (0.35) | PTGS2PTGS1TRPA1PSEN1PSEN2 | |
| SCHEMBL31019954 | 0.80 | EPAS1 (0.36) | PTGS2PTGS1TRPA1PSEN1PSEN2 | |
| SCHEMBL25193465 | 0.78 | MAPK1 (0.38) | PTGS2PTGS1TRPA1PSEN1PSEN2 | |
| SCHEMBL30426876 | 0.78 | MAPK1 (0.38) | PTGS2PTGS1TRPA1PSEN1PSEN2 | |
| SCHEMBL30426697 | 0.78 | MEN1 (0.35) | PTGS2PTGS1 | |
| SCHEMBL30427371 | 0.73 | POLB (0.34) | — | |
| SCHEMBL20530181 | 0.72 | ALDH3A1 (0.40) | — | |
| SCHEMBL25187010 | 0.72 | ALDH3A1 (0.40) | PTGS2PTGS1TRPA1PSEN1PSEN2 | |
| SCHEMBL31019967 | 0.71 | ERN1 (0.40) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118451060-A | Pyrrole derivative or pharmaceutically acceptable salt thereof and composition for preventing, improving or treating gastrointestinal diseases comprising the same as active ingredient | 合娜制药株式会社 | 2024-08-06 | — | — | CN | claimed |
| CN-118451060-A | Pyrrole derivative or pharmaceutically acceptable salt thereof and composition for preventing, improving or treating gastrointestinal diseases comprising the same as active ingredient | 合娜制药株式会社 | 2024-08-06 | — | — | CN | disclosed |