Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.36 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.36 |
| ▸ | KCNQ4 | P56696 | 3/20 | 0.35 |
| ▸ | KCNQ5 | Q9NR82 | 3/20 | 0.35 |
| ▸ | KDM1A | O60341 | 3/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.31 |
| ▸ | QPCT | Q16769 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25247421 | 0.86 | CYP1A2 (0.38) | CYP1A2CYP2C8CYP2B6KCNQ4KCNQ5 | |
| SCHEMBL25287503 | 0.82 | RIPK1 (0.37) | CYP1A2CYP2C8CYP2B6KCNQ4KCNQ5 | |
| SCHEMBL30487405 | 0.79 | NR1D1 (0.40) | CYP1A2CYP2C8CYP2B6KCNQ4KCNQ5 | |
| SCHEMBL25287264 | 0.79 | NR1D1 (0.40) | CYP1A2CYP2C8CYP2B6KCNQ4KCNQ5 | |
| SCHEMBL25247409 | 0.77 | CYP1A2 (0.41) | CYP1A2CYP2C8CYP2B6KCNQ4KCNQ5 | |
| SCHEMBL25290699 | 0.69 | MEN1 (0.42) | CYP1A2CYP2C8CYP2B6RIPK1MEN1 | |
| SCHEMBL25246747 | 0.67 | CYP1A2 (0.59) | CYP1A2CYP2C8CYP2B6KCNQ4KCNQ5 | |
| SCHEMBL18721166 | 0.67 | KCNQ4 (0.43) | KCNQ4KCNQ5KDM1AHDAC8HDAC6 | |
| SCHEMBL3063916 | 0.67 | KCNQ4 (0.43) | KCNQ4KCNQ5KDM1AHDAC8HDAC6 | |
| SCHEMBL25287765 | 0.66 | POLB (0.39) | RIPK1MEN1KMT2APOLBLTB4R2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119948023-A | Regulator containing piperidine polycyclic derivative, preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2025-05-06 | — | — | CN | disclosed |
| CN-118451079-A | Benzopiperidine derivative modulators, methods of preparation and uses thereof | 上海翰森生物医药科技有限公司 | 2024-08-06 | — | — | CN | disclosed |