Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1D1 | P20393 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | KCNQ4 | P56696 | 3/20 | 0.35 |
| ▸ | KCNQ5 | Q9NR82 | 3/20 | 0.35 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.32 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 2/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25287264 | 1.00 | NR1D1 (0.40) | NR1D1POLBATMSMN1; SMN2KCNQ4 | |
| SCHEMBL25287765 | 0.87 | POLB (0.39) | POLBATMSMN1; SMN2RIPK1ALDH1A1 | |
| SCHEMBL25287503 | 0.85 | RIPK1 (0.37) | NR1D1KCNQ4KCNQ5RIPK1ALDH1A1 | |
| SCHEMBL3604936 | 0.79 | MMP1 (0.37) | NR1D1ALDH1A1MAPTLMNACYP2C8 | |
| SCHEMBL31020109 | 0.79 | CYP1A2 (0.36) | POLBKCNQ4KCNQ5RIPK1MEN1 | |
| SCHEMBL25247421 | 0.79 | CYP1A2 (0.38) | KCNQ4KCNQ5RIPK1ALDH1A1MEN1 | |
| SCHEMBL18721167 | 0.76 | NR1D1 (0.47) | NR1D1SMN1; SMN2ALDH1A1MAPTLMNA | |
| SCHEMBL25246740 | 0.75 | CYP1A2 (0.51) | POLBATMSMN1; SMN2KCNQ4KCNQ5 | |
| SCHEMBL31020099 | 0.75 | CYP1A2 (0.51) | POLBATMSMN1; SMN2KCNQ4KCNQ5 | |
| SCHEMBL21051206 | 0.75 | NR1D1 (0.47) | NR1D1POLBATMSMN1; SMN2KCNQ4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023125935-A1 | BENZOPYRIDINE DERIVATIVE REGULATOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 上海翰森生物医药科技有限公司 | 2023-07-06 | — | — | WO | disclosed |