Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | MALT1 | Q9UDY8 | 3/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | FADS1 | O60427 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.39 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23496538 | 1.00 | HTT (0.42) | HTTSMN1; SMN2MAPTKMT2AMEN1 | |
| SCHEMBL21633710 | 0.82 | KMT2A (0.48) | HTTSMN1; SMN2MAPTKMT2AMEN1 | |
| SCHEMBL31020187 | 0.82 | MEN1 (0.46) | HTTSMN1; SMN2MAPTKMT2AMEN1 | |
| SCHEMBL23516703 | 0.82 | MEN1 (0.46) | HTTSMN1; SMN2MAPTKMT2AMEN1 | |
| SCHEMBL31020184 | 0.79 | KMT2A (0.48) | MAPTKMT2AMEN1ALDH1A1IDO1 | |
| SCHEMBL23496549 | 0.79 | KMT2A (0.48) | MAPTKMT2AMEN1ALDH1A1IDO1 | |
| SCHEMBL29656390 | 0.76 | FADS1 (0.44) | HTTSMN1; SMN2MAPTKMT2AMEN1 | |
| SCHEMBL29656234 | 0.76 | FADS1 (0.44) | HTTSMN1; SMN2MAPTKMT2AMEN1 | |
| SCHEMBL30644709 | 0.76 | FADS1 (0.44) | HTTSMN1; SMN2MAPTKMT2AMEN1 | |
| SCHEMBL26597391 | 0.76 | FADS1 (0.44) | HTTSMN1; SMN2MAPTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112638376-B | Substituted tetrahydrocyclopenta [ c ] pyrroles, substituted dihydropyrrolidines, analogs thereof, and methods of use thereof | 爱彼特生物制药公司 | 2024-08-02 | — | — | CN | disclosed |