Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | FADS1 | O60427 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | MALT1 | Q9UDY8 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.45 |
| ▸ | AHR | P35869 | 1/20 | 0.45 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23496549 | 1.00 | KMT2A (0.48) | KMT2AMEN1ALDH1A1MAPTNPC1 | |
| SCHEMBL28571128 | 0.85 | KMT2A (0.47) | KMT2AMEN1ALDH1A1MAPTNPC1 | |
| SCHEMBL21633710 | 0.84 | KMT2A (0.48) | KMT2AMEN1ALDH1A1MAPTNPC1 | |
| SCHEMBL31020187 | 0.81 | MEN1 (0.46) | KMT2AMEN1ALDH1A1MAPTNPC1 | |
| SCHEMBL23516703 | 0.81 | MEN1 (0.46) | KMT2AMEN1ALDH1A1MAPTNPC1 | |
| SCHEMBL31020180 | 0.79 | HTT (0.42) | KMT2AMEN1ALDH1A1MAPTNPC1 | |
| SCHEMBL23496538 | 0.79 | HTT (0.42) | KMT2AMEN1ALDH1A1MAPTNPC1 | |
| SCHEMBL30360009 | 0.75 | NPSR1 (0.55) | KMT2AMEN1ALDH1A1MAPTNPC1 | |
| SCHEMBL28568151 | 0.75 | MAPT (0.51) | KMT2AMEN1ALDH1A1MAPTNPC1 | |
| SCHEMBL23516612 | 0.73 | NPC1 (0.47) | KMT2AMEN1ALDH1A1MAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112638376-B | Substituted tetrahydrocyclopenta [ c ] pyrroles, substituted dihydropyrrolidines, analogs thereof, and methods of use thereof | 爱彼特生物制药公司 | 2024-08-02 | — | — | CN | disclosed |