Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 1/20 | 0.38 |
| ▸ | CA3 | P07451 | 1/20 | 0.30 |
| ▸ | CA6 | P23280 | 1/20 | 0.30 |
| ▸ | CA5A | P35218 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.30 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30881543 | 0.84 | DPP4 (0.31) | — | |
| SCHEMBL28991595 | 0.81 | ERN1 (0.34) | ERN1 | |
| SCHEMBL6470979 | 0.79 | CES2 (0.38) | — | |
| SCHEMBL30986863 | 0.79 | CES2 (0.38) | — | |
| SCHEMBL30504340 | 0.78 | CA3 (0.32) | CA3CA6CA5ACA9CA14 | |
| SCHEMBL29112904 | 0.78 | ERN1 (0.35) | ERN1CA3CA6CA5ACA9 | |
| SCHEMBL615196 | 0.76 | CES2 (0.37) | ERN1 | |
| SCHEMBL23272973 | 0.74 | CA2 (0.36) | ERN1CA3CA6CA5ACA14 | |
| SCHEMBL7628285 | 0.72 | HPGD (0.32) | — | |
| SCHEMBL29263394 | 0.72 | CA1 (0.35) | ERN1CA6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112920183-B | Compounds as KRAS-G12C inhibitors and uses thereof | 南京圣和药业股份有限公司 | 2024-07-19 | — | — | CN | disclosed |