Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY1R | P25929 | 1/20 | 0.46 |
| ▸ | NPY2R | P49146 | 1/20 | 0.46 |
| ▸ | NPY4R | P50391 | 1/20 | 0.46 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.45 |
| ▸ | BACE1 | P56817 | 1/20 | 0.44 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.44 |
| ▸ | ENPEP | Q07075 | 3/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | MME | P08473 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29815391 | 0.90 | NPY4R (0.51) | NPY1RNPY2RNPY4RFOLH1OPRD1 | |
| SCHEMBL30400489 | 0.90 | NPY4R (0.52) | NPY1RNPY2RNPY4RFOLH1OPRD1 | |
| SCHEMBL31345046 | 0.89 | BACE1 (0.53) | NPY1RNPY2RNPY4RBACE1BACE2 | |
| SCHEMBL30445017 | 0.88 | FNTA (0.43) | ENPEP | |
| SCHEMBL30445417 | 0.88 | FNTA (0.43) | ENPEP | |
| SCHEMBL30445727 | 0.88 | FNTA (0.43) | ENPEP | |
| SCHEMBL29478038 | 0.87 | ENPEP (0.45) | ENPEPOPRD1OPRM1MME | |
| SCHEMBL29705780 | 0.87 | OPRD1 (0.54) | NPY1RNPY2RNPY4RFOLH1OPRD1 | |
| SCHEMBL30445795 | 0.86 | OPRD1 (0.44) | BACE1BACE2OPRD1 | |
| SCHEMBL30445776 | 0.86 | OPRD1 (0.44) | BACE1BACE2OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2847223-B2 | ANTI-B7-H6 ANTIBODY, FUSION PROTEINS, AND METHODS OF USING THE SAME | DARTMOUTH COLLEGE (US) | 2025-04-09 | — | — | EP | disclosed |
| US-20250002584-A1 | ANTI-B7-H6 ANTIBODY, FUSION PROTEINS, AND METHODS OF USING THE SAME | DARTMOUTH COLLEGE (US) | 2025-01-02 | — | — | US | disclosed |
| US-12065492-B2 | Anti-B7-H6 antibody, fusion proteins, and methods of using the same | THE TRUSTEES OF DARTMOUTH COLLEGE (US) | 2024-08-20 | — | — | US | disclosed |
| CN-110511278-B | Anti-B7-H6 antibodies, fusion proteins, and methods of use thereof | 达特茅斯大学理事会 | 2024-08-09 | — | — | CN | disclosed |