SCHEMBL29815391

SCHEMBL29815391

CC(C)C[C@H](NC(=O)[C@@H](N)Cc1c[nH]cn1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CS)C(=O)O

nearest known ligand 0.51

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ NPY4R P50391 7/20 0.51
▸ NPY1R P25929 5/20 0.51
▸ NPY2R P49146 3/20 0.51
▸ FOLH1 Q04609 1/20 0.47
▸ OPRM1 P35372 1/20 0.46
▸ OPRD1 P41143 1/20 0.46
▸ NPY5R Q15761 2/20 0.46
▸ ACE P12821 1/20 0.45
▸ MME P08473 3/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30034864 0.91 NPY1R (0.53) NPY4RNPY1RNPY2RFOLH1OPRM1
SCHEMBL30400489 0.91 NPY4R (0.52) NPY4RNPY1RNPY2RFOLH1OPRM1
SCHEMBL31020753 0.90 NPY1R (0.46) NPY4RNPY1RNPY2RFOLH1OPRM1
SCHEMBL29705780 0.90 OPRD1 (0.54) NPY4RNPY1RNPY2RFOLH1OPRM1
SCHEMBL30729668 0.87 FOLH1 (0.53) NPY4RNPY1RNPY2RFOLH1OPRM1
SCHEMBL30729665 0.87 FOLH1 (0.53) NPY4RNPY1RNPY2RFOLH1OPRM1
SCHEMBL29815237 0.87 NPY4R (0.51) NPY4RNPY1RNPY2RFOLH1OPRM1
SCHEMBL29993760 0.87 NPY4R (0.53) NPY4RNPY1RNPY2RFOLH1OPRM1
SCHEMBL30629018 0.87 MME (0.47) NPY4RNPY1RNPY2ROPRM1OPRD1
SCHEMBL3100946 0.86 OPRM1 (0.47) NPY4RNPY1RNPY2RFOLH1OPRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220242964-A1 COMPOSITIONS AND METHODS FOR REGULATING ERYTHROPOIESIS UNIVERSITY OF VIRGINIA PATENT FOUNDATION 2022-08-04 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220242964-A1 COMPOSITIONS AND METHODS FOR REGULATING ERYTHROPOIESIS EPOR, CD47, CD44 NPY4R 2616/4885NPY1R 2794/4885NPY2R 2869/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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