SCHEMBL31020885

CSCC[C@H](N)C(=O)N[C@H](C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@H](C(=O)NCC(=O)N[C@H](C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CS)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@H](C(=O)NCC(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CO)C(=O)O)[C@@H](C)O)C(C)C)[C@@H](C)O)C(C)C

nearest known ligand 0.64

Predicted protein targets (top 8)

	gene	UniProt	supporting neighbours	confidence
▸	IL23R	Q5VWK5	8/20	0.64

▸	CCKBR	P32239	5/20	0.60

▸	GLP1R	P43220	5/20	0.59

▸	GCGR	P47871	1/20	0.59

▸	GIPR	P48546	1/20	0.59

▸	ECE1	P42892	1/20	0.57

▸	MUS81	Q96NY9	1/20	0.57

▸	NR3C1	P04150	2/20	0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL30102558	0.89	IL23R (0.63)	IL23RCCKBRGLP1RECE1MUS81
SCHEMBL30432538	0.89	GLP1R (0.68)	IL23RGLP1RGCGRGIPRECE1
SCHEMBL30906442	0.88	GLP1R (0.66)	IL23RCCKBRGLP1RGCGRGIPR
SCHEMBL30906466	0.88	GLP1R (0.66)	IL23RCCKBRGLP1RGCGRGIPR
SCHEMBL38663457	0.88	KEAP1 (0.57)	IL23RCCKBRGLP1RECE1MUS81
SCHEMBL31683350	0.87	CCKBR (0.65)	IL23RCCKBRGLP1RGCGRGIPR
SCHEMBL31666090	0.86	GLP1R (0.66)	IL23RCCKBRGLP1RGCGRGIPR
SCHEMBL30690372	0.86	GLP1R (0.66)	IL23RCCKBRGLP1RECE1MUS81
SCHEMBL30690358	0.86	GLP1R (0.66)	IL23RCCKBRGLP1RECE1MUS81
SCHEMBL30648454	0.86	GLP1R (0.69)	IL23RCCKBRGLP1RGCGRGIPR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-11999775-B2	VEGF-binding protein for blockade of angiogenesis	CHILDREN'S MEDICAL CENTER CORPORATION (US)	2024-06-04	—	—	US	disclosed