Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKZF1 | Q13422 | 5/20 | 0.73 |
| ▸ | IKZF2 | Q9UKS7 | 15/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21340234 | 1.00 | IKZF1 (0.73) | IKZF1IKZF2 | |
| SCHEMBL20765782 | 0.93 | IKZF1 (0.74) | IKZF1IKZF2 | |
| SCHEMBL31021063 | 0.93 | IKZF1 (0.74) | IKZF1IKZF2 | |
| SCHEMBL20765766 | 0.91 | IKZF2 (0.73) | IKZF1IKZF2 | |
| SCHEMBL23306213 | 0.88 | IKZF1 (0.68) | IKZF1IKZF2 | |
| SCHEMBL24856642 | 0.88 | IKZF1 (0.68) | IKZF1IKZF2 | |
| SCHEMBL29712440 | 0.88 | IKZF1 (0.68) | IKZF1IKZF2 | |
| SCHEMBL20765247 | 0.87 | IKZF1 (0.78) | IKZF1IKZF2 | |
| SCHEMBL20765272 | 0.87 | IKZF1 (0.78) | IKZF1IKZF2 | |
| SCHEMBL20765168 | 0.87 | IKZF1 (0.78) | IKZF1IKZF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240384007-A1 | COMPOSITIONS AND METHODS FOR SELECTIVE PROTEIN DEGRADATION | NOVARTIS AG (CH) | 2024-11-21 | — | — | US | disclosed |
| US-11999802-B2 | Compositions and methods for selective protein degradation | NOVARTIS AG (CH) | 2024-06-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240384007-A1 | COMPOSITIONS AND METHODS FOR SELECTIVE PROTEIN DEGRADATION | CRBN, RPS27A, COPB1 | IKZF1 781/4885IKZF2 336/4885 |
| US-11999802-B2 | Compositions and methods for selective protein degradation | CRBN, RPS27A, COPB1 | IKZF1 781/4885IKZF2 336/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.