Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.33 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1530313 | 0.84 | CRBN (0.61) | CRBNCYP3A4MTNR1AHPGDKDM4E | |
| SCHEMBL2910151 | 0.80 | CRBN (0.43) | CRBNCYP3A4 | |
| SCHEMBL2915298 | 0.79 | CRBN (0.56) | CRBNCYP3A4ALDH2HPGDKDM4E | |
| SCHEMBL2913931 | 0.77 | CRBN (0.69) | CRBNCYP3A4 | |
| Water SCHEMBL2915433 | 0.76 | CRBN (0.68) | CRBNCYP3A4 | |
| Methyl Alcohol SCHEMBL2913736 | 0.76 | CRBN (0.67) | CRBNCYP3A4 | |
| Alcohol SCHEMBL2909873 | 0.75 | CRBN (0.64) | CRBNCYP3A4 | |
| SCHEMBL2913195 | 0.75 | CA2 (0.31) | — | |
| SCHEMBL2915236 | 0.74 | CRBN (0.46) | CRBNCYP3A4 | |
| SCHEMBL2907863 | 0.74 | CRBN (0.42) | CRBNCYP3A4HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2222646-A1 | URACIL OR THYMINE DERIVATIVE FOR TREATING HEPATITIS C | Abbott Laboratories (US) | 2010-09-01 | — | — | EP | disclosed |
| WO-2009039127-A1 | URACIL OR THYMINE DERIVATIVE FOR TREATING HEPATITIS C | ABBOTT LABORATORIES (US) | 2009-03-26 | — | — | WO | disclosed |