Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.40 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | GRM5 | P41594 | 5/20 | 0.38 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.32 |
| ▸ | KMO | O15229 | 1/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL670749 | 0.80 | FFAR1 (0.37) | FFAR1EGFRERBB2 | |
| SCHEMBL708798 | 0.78 | FFAR1 (0.56) | TRPV3FFAR1GRM5TRPV1 | |
| SCHEMBL3245685 | 0.74 | ALDH1A1 (0.46) | PTGDR2TRPV3FFAR1GRM5NR3C2 | |
| SCHEMBL13989104 | 0.71 | FFAR1 (0.43) | FFAR1GRM5 | |
| SCHEMBL4865263 | 0.71 | GRM5 (0.50) | FFAR1GRM5 | |
| SCHEMBL12537945 | 0.68 | TRPV3 (0.46) | PTGDR2TRPV3GRM5NR3C2 | |
| SCHEMBL13138542 | 0.68 | FFAR1 (0.44) | FFAR1GRM5 | |
| SCHEMBL10020217 | 0.67 | GRM4 (0.64) | FFAR1GRM5 | |
| SCHEMBL3753115 | 0.66 | CYP11B2 (0.58) | KMO | |
| SCHEMBL29998142 | 0.66 | CYP11B2 (0.58) | KMO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2217600-B1 | FUNGICIDAL BICYCLIC PYRAZOLES | DU PONT (US) | 2012-12-05 | — | — | EP | disclosed |
| US-8288375-B2 | Fungicidal bicyclic pyrazoles | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2012-10-16 | — | — | US | disclosed |
| US-20100273775-A1 | FUNGICIDAL BICYCLIC PYRAZOLES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2010-10-28 | — | — | US | disclosed |
| EP-2217600-A2 | FUNGICIDAL BICYCLIC PYRAZOLES | E. I. du Pont de Nemours and Company (US) | 2010-08-18 | — | — | EP | disclosed |
| WO-2009076440-A2 | FUNGICIDAL BICYCLIC PYRAZOLES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2009-06-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100273775-A1 | FUNGICIDAL BICYCLIC PYRAZOLES | CYP1B1, CBR1, CYP1A1 | PTGDR2 2840/4885TRPV3 2741/4885FFAR1 1476/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.