Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 11/20 | 0.57 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.44 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.42 |
| ▸ | SERPINH1 | P50454 | 1/20 | 0.42 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.40 |
| ▸ | AXL | P30530 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23622948 | 0.83 | F7 (0.51) | NR4A2 | |
| SCHEMBL30993716 | 0.82 | CREBBP (0.41) | NR4A2CREBBPKMT2AMTNR1AMTNR1B | |
| SCHEMBL19644378 | 0.79 | NR4A2 (0.61) | NR4A2CREBBPCHEK1MAP2K1AXL | |
| SCHEMBL20604733 | 0.78 | NR4A2 (0.46) | NR4A2CREBBPMAP2K1 | |
| SCHEMBL17113293 | 0.76 | NR4A2 (0.70) | NR4A2CREBBPMAP2K1AXL | |
| SCHEMBL1078500 | 0.75 | NR4A2 (0.51) | NR4A2CREBBPCHEK1SERPINH1MEN1 | |
| SCHEMBL19644386 | 0.73 | NR4A2 (0.54) | NR4A2CREBBPMAP2K1AXL | |
| SCHEMBL15300951 | 0.73 | NR4A2 (0.61) | NR4A2CREBBP | |
| SCHEMBL4242189 | 0.73 | NR4A2 (1.00) | NR4A2CREBBP | |
| SCHEMBL610371 | 0.73 | ABL1 (0.64) | NR4A2CHEK1MEN1KMT2AABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024130095-A9 | COMPOUNDS AND COMPOSITIONS AS CBP/P300 DEGRADERS AND USES THEREOF | REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2024-08-02 | — | — | WO | disclosed |