SCHEMBL610371

SCHEMBL610371

COC(=O)c1ccc(Cl)cc1Br

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ABL1 P00519 1/20 0.64
NR4A2 P43354 2/20 0.51
FLT1 P17948 2/20 0.50
FLT4 P35916 2/20 0.50
KDR P35968 2/20 0.50
SLC6A4 P31645 1/20 0.47
SLC6A3 Q01959 1/20 0.47
RXFP1 Q9HBX9 1/20 0.47
MAPT P10636 3/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
NPC1 O15118 1/20 0.46
NFKB1 P19838 1/20 0.46
RAB9A P51151 1/20 0.46
NFKB2 Q00653 1/20 0.46
RELA Q04206 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
ALDH1A1 P00352 4/20 0.46
CA12 O43570 1/20 0.46
CA1 P00915 1/20 0.46
CA2 P00918 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL852809 0.85 ABL1 (0.59) ABL1NR4A2SLC6A4SLC6A3RXFP1
SCHEMBL29972294 0.83 ABL1 (0.47) ABL1NR4A2FLT1FLT4KDR
SCHEMBL6100118 0.82 ABL1 (0.70) ABL1NR4A2FLT1FLT4KDR
SCHEMBL31289941 0.82 ABL1 (0.51) ABL1NR4A2SLC6A4SLC6A3RXFP1
SCHEMBL3839211 0.81 NR4A2 (0.54) ABL1NR4A2FLT1FLT4KDR
SCHEMBL608814 0.81 ABL1 (0.68) ABL1NR4A2FLT1FLT4KDR
SCHEMBL5099711 0.81 MAOB (0.53) RXFP1CA12CA1CA2CA7
SCHEMBL22366366 0.81 FLT1 (0.43) ABL1FLT1FLT4KDRMAPT
SCHEMBL1016173 0.79 ABL1 (0.66) ABL1NR4A2FLT1FLT4KDR
SCHEMBL70233 0.79 KDM4E (0.62) MAPTSMN1; SMN2ALDH1A1CA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 253 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4063466-B1 ORGANIC OPTOELECTRONIC DEVICE, AND DISPLAY DEVICE INCLUDING SAME SAMSUNG SDI CO LTD (KR) 2026-04-01 EP disclosed
EP-4644378-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DIODE USING SAME Solus Advanced Materials Co., Ltd. (KR) 2025-11-05 EP disclosed
US-20250331418-A1 ORGANIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME SFC CO., LTD. (KR) 2025-10-23 US disclosed
CN-120554197-A Synthesis method of (R) -1- (2-bromo-4-chlorophenyl) -2, 2-trifluoroethanol 苏州汉德创宏生化科技有限公司 2025-08-29 CN disclosed
US-12398120-B2 Substituted hydantoinamides as ADAMTS7 antagonists BAYER AKTIENGESELLSCHAFT (DE) 2025-08-26 US disclosed
US-12378204-B2 Triazole compounds and preparation method therefor and use thereof WUHAN LL SCIENCE AND TECHNOLOGY DEVELOPMENT CO., LTD. (CN) 2025-08-05 US disclosed
US-20250195483-A1 SPIRO PIPERIDINE DERIVATIVES AS INHIBITORS OF APOL1 AND METHODS OF USING SAME VERTEX PHARMA (US) 2025-06-19 US disclosed
WO-2025081019-A1 KIF MODULATOR COMPOUNDS AND METHODS OF USE IAMBIC THERAPEUTICS, INC. (US) 2025-04-17 WO disclosed
EP-4520755-A1 ORGANIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME SFC Co., Ltd. (KR) 2025-03-12 EP disclosed
CN-119569635-A Biaryl ring inhibitors targeting c-Myc proteins 上海深势唯思科技有限责任公司 2025-03-07 CN disclosed
WO-2004050650-A1 ANILINOPYRAZOLE DERIVATIVES USEFUL FOR THE TREATMENT OF DIABETES BAYER PHARMACEUTICALS CORPORATION (US) 2004-06-17 WO disclosed
WO-2004050651-A1 ANILINOPYRAZOLE DERIVATIVES USEFUL FOR THE TREATMENT OF DIABETES BAYER PHARMACEUTICALS CORPORATION (US) 2004-06-17 WO disclosed
EP-0734380-B1 4-BENZOYLISOXAZOLES AND THEIR USE AS HERBICIDES AVENTIS AGRICULTURE LTD (GB) 2002-07-10 EP disclosed
US-6369270-B1 CHEMICAL INTERMEDIATES RHONE POULENC AGRICULTURE LIMITED (GB) 2002-04-09 US disclosed
US-6114538-A 2-POSITION OF BENZOY RING OF 4-BENZOYLISOXAZOLE DERIVATIVE IS SUBSTITUTED AND PARTICULARLY USED AGAINST MONOCOTYLEDONOUS WEEDS BY POST-EMEREGENECE APPLICATION RHONE POULENC AGRICULTURE LIMITED (GB) 2000-09-05 US disclosed
US-5998653-A CHEMICAL INTERMEDIATE FOR HERBICIDES RHONE POULENC AGRICULTURE LIMITED (GB) 1999-12-07 US disclosed
US-5658858-A POSTEMERGENCE HERBICIDES RHONE-POULENC ARGRICULTURE LIMITED (GB) 1997-08-19 US disclosed
EP-0734380-A1 4-BENZOYLISOXAZOLES AND THEIR USE AS HERBICIDES RHONE-POULENC AGRICULTURE LTD. (GB) 1996-10-02 EP disclosed
WO-1995016678-A1 4-BENZOYLISOXAZOLES AND THEIR USE AS HERBICIDES RHONE POULENC AGRICULTURE LIMITED (GB) 1995-06-22 WO disclosed
US-3966728-A ANTIPEPTIC ULCER ACTIVITY NIPPON SHINYAKU CO., LTD. (JA) 1976-06-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250331418-A1 ORGANIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME LOXL1, PPOX, AOX1 ABL1 2390/4885NR4A2 1353/4885FLT1 3770/4885
US-20250195483-A1 SPIRO PIPERIDINE DERIVATIVES AS INHIBITORS OF APOL1 AND METHODS OF USING SAME APOL1, PNLIP, SAAL1 ABL1 2734/4885NR4A2 1824/4885FLT1 2414/4885
US-12398120-B2 Substituted hydantoinamides as ADAMTS7 antagonists ADAMTS7, MMP7, ADAM17 ABL1 2705/4885NR4A2 3120/4885FLT1 172/4885
US-12378204-B2 Triazole compounds and preparation method therefor and use thereof LPAR1, LPAR3, FFAR1 ABL1 2207/4885NR4A2 2754/4885FLT1 1720/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.