Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 7/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | NPC1 | O15118 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.61 |
| ▸ | RAB9A | P51151 | 1/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.60 |
| ▸ | CDK2 | P24941 | 1/20 | 0.60 |
| ▸ | SIGLEC9 | Q9Y336 | 2/20 | 0.57 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.56 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.56 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.49 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.49 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.49 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1876139 | 1.00 | GPR119 (0.65) | GPR119ALDH1A1NPC1MAPTMAPK1 | |
| SCHEMBL29485617 | 0.93 | GPR119 (0.59) | GPR119ALDH1A1NPC1MAPTMAPK1 | |
| SCHEMBL23022528 | 0.93 | GPR119 (0.59) | GPR119ALDH1A1NPC1MAPTMAPK1 | |
| SCHEMBL29485608 | 0.93 | GPR119 (0.59) | GPR119ALDH1A1NPC1MAPTMAPK1 | |
| SCHEMBL23022526 | 0.93 | GPR119 (0.59) | GPR119ALDH1A1NPC1MAPTMAPK1 | |
| SCHEMBL23022524 | 0.93 | GPR119 (0.59) | GPR119ALDH1A1NPC1MAPTMAPK1 | |
| SCHEMBL22686681 | 0.86 | EPHX2 (0.68) | GPR119ALDH1A1NPC1MAPTMAPK1 | |
| SCHEMBL3963092 | 0.85 | ALDH1A1 (0.71) | GPR119ALDH1A1NPC1MAPTMAPK1 | |
| SCHEMBL1879959 | 0.85 | ALDH1A1 (0.64) | GPR119ALDH1A1NPC1MAPTMAPK1 | |
| SCHEMBL2709640 | 0.85 | ALDH1A1 (0.74) | GPR119ALDH1A1NPC1MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4665718-A1 | SMALL MOLECULES AS MONOACYLGLYCEROL LIPASE (MAGL) INHIBITORS, COMPOSITIONS AND USE THEREOF | Apogee Pharmaceuticals, Inc. (CA) | 2025-12-24 | — | — | EP | disclosed |
| WO-2024168426-A1 | SMALL MOLECULES AS MONOACYLGLYCEROL LIPASE (MAGL) INHIBITORS, COMPOSITIONS AND USE THEREOF | APOGEE PHARMACEUTICALS, INC. (CA) | 2024-08-22 | — | — | WO | disclosed |