Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.48 |
| ▸ | LTB4R | Q15722 | 6/20 | 0.45 |
| ▸ | LTB4R2 | Q9NPC1 | 6/20 | 0.45 |
| ▸ | HTR6 | P50406 | 4/20 | 0.43 |
| ▸ | HTR2C | P28335 | 2/20 | 0.42 |
| ▸ | HTR2B | P41595 | 2/20 | 0.42 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | HTR1D | P28221 | 1/20 | 0.38 |
| ▸ | HTR1B | P28222 | 1/20 | 0.38 |
| ▸ | HTR1F | P30939 | 1/20 | 0.38 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.38 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.37 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.37 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.37 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.37 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31024320 | 0.88 | HTR2A (0.48) | HTR2ALTB4RLTB4R2HTR6HTR2C | |
| SCHEMBL31024318 | 0.87 | HTR2A (0.49) | HTR2ALTB4RLTB4R2HTR6HTR2C | |
| SCHEMBL31417623 | 0.83 | HTR6 (0.55) | HTR2ALTB4RLTB4R2HTR6HTR2C | |
| SCHEMBL31024317 | 0.82 | HTR2A (0.56) | HTR2AHTR6HTR2CHTR2BHTR1A | |
| SCHEMBL31666414 | 0.79 | HTR2A (0.55) | HTR2AHTR6HTR2CHTR2BHTR1A | |
| SCHEMBL23805253 | 0.79 | HTR2A (0.56) | HTR2ALTB4RLTB4R2HTR6HTR2C | |
| SCHEMBL31506467 | 0.79 | GHSR (0.43) | HTR2ALTB4RLTB4R2HTR6ABCG2 | |
| SCHEMBL30859499 | 0.78 | HTR6 (0.52) | HTR6HTR1AHTR1DHTR1BHTR1F | |
| SCHEMBL24877696 | 0.78 | HTR6 (0.52) | HTR6HTR1AHTR1DHTR1BHTR1F | |
| SCHEMBL12558831 | 0.77 | HTR2C (0.61) | HTR2ALTB4RLTB4R2HTR6HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4655282-A1 | 3-(2-(DIMETHYLAMINO)ETHYL)-1H-INDOL-4-YL DERIVATIVES | COMPASS Pathfinder Limited (GB) | 2025-12-03 | — | — | EP | disclosed |
| US-20240269113-A1 | 3-(2-(DIMETHYLAMINO)ETHYL)-1H-INDOL-4-yl DERIVATIVES | COMPASS PATHFINDER LIMITED (GB) | 2024-08-15 | — | — | US | disclosed |
| WO-2024156732-A1 | 3-(2-(DIMETHYLAMINO)ETHYL)-1H-INDOL-4-YL DERIVATIVES | COMPASS PATHFINDER LIMITED (GB) | 2024-08-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240269113-A1 | 3-(2-(DIMETHYLAMINO)ETHYL)-1H-INDOL-4-yl DERIVATIVES | HTR2C, HTR2A, HTR1A | HTR2A 2/4885LTB4R 631/4885LTB4R2 431/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.