Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 10/20 | 0.37 |
| ▸ | EED | O75530 | 1/20 | 0.37 |
| ▸ | RBBP4 | Q09028 | 1/20 | 0.37 |
| ▸ | SUZ12 | Q15022 | 1/20 | 0.37 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.37 |
| ▸ | AEBP2 | Q6ZN18 | 1/20 | 0.37 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25344433 | 0.90 | GPR119 (0.40) | GPR119HRH3USP2SMN1; SMN2SCD5 | |
| SCHEMBL31024670 | 0.85 | GPR119 (0.46) | PKMGPR119EEDRBBP4SUZ12 | |
| SCHEMBL31738795 | 0.81 | PKM (0.40) | PKMGPR119EEDRBBP4SUZ12 | |
| SCHEMBL31024699 | 0.80 | EED (0.40) | PKMGPR119EEDRBBP4SUZ12 | |
| SCHEMBL31024694 | 0.76 | GPR119 (0.42) | PKMGPR119EEDRBBP4SUZ12 | |
| SCHEMBL25342552 | 0.75 | KMT2A (0.49) | PKMGPR119SMN1; SMN2 | |
| SCHEMBL25343723 | 0.75 | GPR119 (0.49) | GPR119HRH3USP2SMN1; SMN2 | |
| SCHEMBL31024717 | 0.74 | GPR119 (0.43) | PKMGPR119EEDRBBP4SUZ12 | |
| SCHEMBL23044100 | 0.73 | ESR2 (0.56) | PKMGPR119EEDRBBP4SUZ12 | |
| SCHEMBL25342059 | 0.72 | IDO1 (0.47) | PKMGPR119EEDRBBP4SUZ12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4656642-A1 | ESTROGEN RECEPTOR PROTEOLYSIS TARGETING CHIMERA COMPOUND AND USE THEREOF | GAN & LEE PHARM CO., LTD (CN) | 2025-12-03 | — | — | EP | disclosed |
| WO-2024156294-A1 | ESTROGEN RECEPTOR PROTEOLYSIS TARGETING CHIMERA COMPOUND AND USE THEREOF | 甘李药业股份有限公司 | 2024-08-02 | — | — | WO | disclosed |