Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 2/20 | 0.55 |
| ▸ | PRKDC | P78527 | 4/20 | 0.51 |
| ▸ | GAK | O14976 | 1/20 | 0.49 |
| ▸ | EP300 | Q09472 | 1/20 | 0.46 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.46 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.46 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.46 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.45 |
| ▸ | MTOR | P42345 | 1/20 | 0.45 |
| ▸ | LGMN | Q99538 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2879730 | 0.91 | AR (0.48) | ARPRKDCGAKEP300KAT2B | |
| SCHEMBL28317359 | 0.82 | HRH4 (0.57) | ALDH1A1MAPTKMT2AKDM4E | |
| SCHEMBL27743819 | 0.81 | LMNA (0.52) | ARPRKDCGAKEP300KAT2B | |
| SCHEMBL7607968 | 0.81 | DRD3 (0.57) | MEN1MAPTKMT2ALMNACYP2E1 | |
| SCHEMBL13118688 | 0.81 | ADRB1 (0.50) | ALDH1A1LMNAKDM4EHSD17B10USP2 | |
| SCHEMBL13735487 | 0.79 | AR (0.49) | ARPRKDCGAKEP300KAT2B | |
| SCHEMBL5499160 | 0.78 | SYK (0.53) | ARGAKNPC1MAPTRAB9A | |
| SCHEMBL9093746 | 0.76 | LMNA (0.71) | PRKDCEP300KAT2BPIK3CAPIK3CG | |
| SCHEMBL5133066 | 0.75 | LMNA (0.72) | ARPRKDCALDH1A1MEN1NPC1 | |
| SCHEMBL31025628 | 0.75 | MAPT (0.49) | EP300KAT2BALDH1A1NPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107898790-B | Antiviral JAK inhibitors for the treatment or prevention of retroviral and other viral infections | 埃默里大学 | 2024-06-21 | — | — | CN | disclosed |