SCHEMBL31026388

SCHEMBL31026388

CCCCCCCCCCCCSC(=O)C(C)(C)C

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 6/20 0.45
HSD17B10 Q99714 2/20 0.45
GMNN O75496 1/20 0.45
TP53 P04637 1/20 0.45
POLB P06746 1/20 0.45
MAPT P10636 1/20 0.45
THRB P10828 1/20 0.45
CYP2C9 P11712 1/20 0.45
BLM P54132 1/20 0.45
CES1 P23141 7/20 0.44
FAAH O00519 4/20 0.44
PLA2G6 O60733 1/20 0.44
ACHE P22303 3/20 0.42
EPHX1 P07099 1/20 0.41
ASAH1 Q13510 1/20 0.40
PPARG P37231 4/20 0.38
PPARD Q03181 4/20 0.38
PPARA Q07869 4/20 0.38
TSHR P16473 3/20 0.38
GPR84 Q9NQS5 3/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3869805 1.00 CES2 (0.45) CES2HSD17B10GMNNTP53POLB
SCHEMBL22951373 1.00 CES2 (0.45) CES2HSD17B10GMNNTP53POLB
SCHEMBL22951385 1.00 CES2 (0.45) CES2HSD17B10GMNNTP53POLB
SCHEMBL22951375 1.00 CES2 (0.45) CES2HSD17B10GMNNTP53POLB
SCHEMBL3864583 0.98 CES2 (0.42) CES2HSD17B10GMNNTP53POLB
SCHEMBL3866692 0.91 NOS3 (0.43) CES2HSD17B10GMNNTP53POLB
SCHEMBL9949444 0.85 FAAH (0.56) CES2HSD17B10CES1FAAHPLA2G6
SCHEMBL22955375 0.83 CES2 (0.42) CES2HSD17B10GMNNTP53POLB
SCHEMBL22956016 0.83 CES2 (0.42) CES2HSD17B10GMNNTP53POLB
SCHEMBL3864690 0.81 TDP1 (0.50) CES1TSHRALDH1A1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118637970-A Method for producing thioester derivative, method for producing ketone derivative, and method for producing aldehyde derivative 株式会社德山 2024-09-13 CN disclosed