Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10746176 | 0.98 | MAPT (0.48) | MAPTAPPBACE1BACE2TSHR | |
| SCHEMBL17110173 | 0.77 | MAPT (0.47) | MAPTLMNAALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL17358748 | 0.76 | MAPT (0.50) | MAPTLMNAPOLBGAAALDH1A1 | |
| SCHEMBL1263344 | 0.76 | MAPT (0.39) | MAPTAPPBACE1BACE2TSHR | |
| SCHEMBL1262497 | 0.74 | MAPT (0.36) | MAPTAPPBACE1BACE2TSHR | |
| SCHEMBL4005170 | 0.74 | MAPT (0.44) | MAPT | |
| SCHEMBL1264136 | 0.71 | MAPT (0.69) | MAPTTSHRMAP3K14ALDH1A1 | |
| SCHEMBL21677137 | 0.71 | MAPT (0.62) | MAPTMAP3K14LMNAPOLBGAA | |
| SCHEMBL17358726 | 0.70 | KMT2A (0.46) | MAPTTSHRPOLBALDH1A1KMT2A | |
| SCHEMBL7060319 | 0.69 | LMNA (0.36) | MAPTAPPBACE1BACE2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118222769-A | Multi-carboxylic acid group high-absorption chrome tanning auxiliary agent containing barbituric acid structure and preparation method thereof | 南京工业大学 | 2024-06-21 | — | — | CN | disclosed |