SCHEMBL1263344

SCHEMBL1263344

CN1C(=O)C(C2CCCCC2)C(=O)N(C)C1=O

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.39
ALDH1A1 P00352 7/20 0.34
APP P05067 1/20 0.33
BACE1 P56817 1/20 0.33
BACE2 Q9Y5Z0 1/20 0.33
GSK3A P49840 2/20 0.32
GSK3B P49841 2/20 0.32
HSD11B1 P28845 1/20 0.32
TSHR P16473 1/20 0.32
KMT2A Q03164 5/20 0.31
POLB P06746 2/20 0.31
MEN1 O00255 2/20 0.31
PKM P14618 1/20 0.31
LMNA P02545 2/20 0.31
GAA P10253 1/20 0.31
SMN1; SMN2 Q16637 2/20 0.31
CYP2C9 P11712 2/20 0.31
CYP2C19 P33261 2/20 0.31
CYP3A4 P08684 1/20 0.31
MAPK1 P28482 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1262497 0.98 MAPT (0.36) MAPTALDH1A1APPBACE1BACE2
SCHEMBL21292115 0.82 TSHR (0.40) MAPTALDH1A1APPBACE1BACE2
SCHEMBL7717193 0.81 PLG (0.32) MAPT
SCHEMBL15679912 0.80 MAPK1 (0.34) MAPTALDH1A1MAPK1
SCHEMBL4005170 0.80 MAPT (0.44) MAPT
SCHEMBL7717214 0.79 PLG (0.35) MAPTALDH1A1
SCHEMBL31026682 0.76 MAPT (0.52) MAPTALDH1A1APPBACE1BACE2
SCHEMBL10746176 0.74 MAPT (0.48) MAPTALDH1A1APPBACE1BACE2
SCHEMBL17300501 0.72 BBOX1 (0.46) MAPTALDH1A1KMT2APOLBLMNA
SCHEMBL7720030 0.72 PLG (0.30) MAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 246 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9668943-B2 Dental conditioning composition KABUSHIKI KAISHA SHOFU (JP) 2017-06-06 US claimed
US-6784224-B2 STORAGE STABLE, GELATION INHIBITION, CONSISTS OF (METH)ACRYLATE MONOMERS, A FILLER AND A PYRIMIDINETRIONES CATALYST; MULTI-PASTES CONTAINS DIFFERENT COMPONENTS, MIXED WITH EACH OTHER TO POLYMERIZE; DENTAL ADHESIVES GC CORPORATION (JP) 2004-08-31 US claimed
US-20260144715-A1 DENTAL CURABLE COMPOSITION HAVING HIGH MECHANICAL STRENGTH SHOFU INC. (JP) 2026-05-28 US disclosed
US-12622847-B2 Organosilicon compound and dental composition containing same KURARAY NORITAKE DENTAL INC. (JP) 2026-05-12 US disclosed
EP-4717251-A2 DENTAL CURABLE COMPOSITION HAVING HIGH MECHANICAL STRENGTH Shofu Inc. (JP) 2026-04-01 EP disclosed
US-20260069510-A1 DENTAL RESIN-REINFORCED GLASS IONOMER CEMENT COMPOSITION SHOFU INC. (JP) 2026-03-12 US disclosed
EP-3733152-B1 POWDER-LIQUID TYPE RESIN-REINFORCED DENTAL GLASS IONOMER CEMENT COMPOSITION SHOFU INC (JP) 2026-03-11 EP disclosed
US-20260060900-A1 DENTAL COMPOSITE RESIN KIT SHOFU INC. (JP) 2026-03-05 US disclosed
EP-4659729-A1 DENTAL RESIN-REINFORCED GLASS IONOMER CEMENT COMPOSITION Shofu Inc. (JP) 2025-12-10 EP disclosed
US-12465559-B2 Fluorescent curable dental composition and cured product thereof KURARAY NORITAKE DENTAL INC. (JP) 2025-11-11 US disclosed
US-20250213434-A1 DENTAL CURABLE COMPOSITION HAVING FAVORABLE COLOR COMPATIBILITY KURARAY NORITAKE DENTAL INC. (JP) 2025-07-03 US disclosed
EP-0702948-B1 TOOTH SURFACE TREATING AGENT SHOFU KK (JP) 2001-03-07 EP disclosed
EP-1066813-A2 Dental adhesive composition KABUSHIKI KAISHA SHOFU (JP) 2001-01-10 EP disclosed
EP-1056432-A1 IMPROVED CATALYTIC POLYMERIZATION ACCELERATOR SYSTEMS Mycone Dental Supply Company, Inc. (US) 2000-12-06 EP disclosed
WO-1999043288-A1 IMPROVED CATALYTIC POLYMERIZATION ACCELERATOR SYSTEMS MYCONE DENTAL SUPPLY COMPANY, INC. (US) 1999-09-02 WO disclosed
US-5883153-A SUSTAINED RELEASE GLASS IONOMERS SHOFU INC. (JP) 1999-03-16 US disclosed
US-5707611-A Tooth surface treating agent KABUSHIKI KAISHA SHOFU (JP) 1998-01-13 US disclosed
EP-0702948-A1 TOOTH SURFACE TREATMENT KABUSHIKI KAISHA SHOFU (JP) 1996-03-27 EP disclosed
EP-0694298-A1 PREFORMED GLASS IONOMER FILLER WHICH CAN SUSTAINEDLY RELEASE FLUORIDE ION AND DENTAL COMPOSITION CONTAINING THE SAME SHOFU INC. (JP) 1996-01-31 EP disclosed
US-5264513-A Dental adhesive KABUSHIKI KAISHA SHOFU (JP) 1993-11-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260069510-A1 DENTAL RESIN-REINFORCED GLASS IONOMER CEMENT COMPOSITION GRIN3A, HBG1, ASIC1 MAPT 2952/4885ALDH1A1 3441/4885APP 4026/4885
US-20260060900-A1 DENTAL COMPOSITE RESIN KIT BOLA2; BOLA2B, LBR, COL2A1 MAPT 2976/4885ALDH1A1 314/4885APP 4189/4885
US-12465559-B2 Fluorescent curable dental composition and cured product thereof BRD1, TBCA, BAZ1A MAPT 1437/4885ALDH1A1 1780/4885APP 4217/4885
US-20260144715-A1 DENTAL CURABLE COMPOSITION HAVING HIGH MECHANICAL STRENGTH CAD, SMCHD1, ITGA1 MAPT 991/4885ALDH1A1 1523/4885APP 2054/4885
US-12622847-B2 Organosilicon compound and dental composition containing same MSL1, ITGA1, ITGAL MAPT 4304/4885ALDH1A1 668/4885APP 3474/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.